Stephenson H, Dotters D J, Katz V, Droegemueller W
Department of Obstetrics and Gynecology, School of Medicine, University of North Carolina, Chapel Hill 27599.
Am J Obstet Gynecol. 1992 May;166(5):1324-7. doi: 10.1016/0002-9378(92)91597-4.
We attempted to characterize the natural history of necrotizing fasciitis of the vulva.
The records of 29 nonpregnant women with necrotizing fasciitis of the vulva were evaluated.
These women experienced a rapidly progressing polymicrobial infection. Initially, the infections in many women were thought to be labial cellulitis, appearing mild and innocuous. Delays in recognition and aggressive surgical management were associated with increased morbidity and mortality. Of 15 women with a delay greater than 48 hours between presentation and treatment, 11 died. Twenty of 29 (69%) were diabetic, accounting for 11 of the 14 deaths.
Early diagnosis and aggressive surgical debridement in spite of mild symptoms will improve outcome in this serious disease process.
我们试图描述外阴坏死性筋膜炎的自然病程。
对29例非妊娠外阴坏死性筋膜炎女性患者的记录进行评估。
这些女性经历了快速进展的多微生物感染。最初,许多女性的感染被认为是阴唇蜂窝织炎,表现轻微且无害。识别延迟和积极的手术治疗与发病率和死亡率增加有关。在15例就诊与治疗间隔超过48小时的女性中,11例死亡。29例中有20例(69%)患有糖尿病,14例死亡患者中有11例患有糖尿病。
尽管症状轻微,但早期诊断和积极的手术清创将改善这种严重疾病过程的预后。