Nakayama John, Busse Raydeen
Duke University Medical Center, Durham, NC, USA.
Hawaii Med J. 2010 Jan;69(1):13-6.
Vulvar necrotizing fasciitis is a surgical emergency with a high rate of morbidity and mortality. Our case series adds seven patients to the literature and presents the first group that is predominantly of Pacific-Islander origin. This study not only confirms traditional risk factors such as diabetes mellitus, obesity and hypertension but investigates ethnicity and socioeconomic status as risk factors. Also presented is a case of recurrent necrotizing fasciitis initially involving the vulva, then the back. In any patient for which there is suspicion of vulvar necrotizing fasciitis, surgical diagnosis remains the gold standard and facilitates rapid debridement of all necrotic tissues. Aggressive surgical debridement with broad spectrum antibiotic coverage is required to minimize mortality.
外阴坏死性筋膜炎是一种具有高发病率和死亡率的外科急症。我们的病例系列为文献增添了7例患者,并展示了首个以太平洋岛民为主的群体。本研究不仅证实了糖尿病、肥胖症和高血压等传统风险因素,还调查了种族和社会经济地位作为风险因素。此外还介绍了一例复发性坏死性筋膜炎的病例,最初累及外阴,随后累及背部。对于任何怀疑患有外阴坏死性筋膜炎的患者,手术诊断仍然是金标准,有助于迅速清除所有坏死组织。需要进行积极的手术清创并使用广谱抗生素以将死亡率降至最低。