Buchanan Greg O, Williams Philip G, Feling Robert H, Kauffman Christopher A, Jensen Paul R, Fenical William
Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California-San Diego, La Jolla, California 92093-0204, USA.
Org Lett. 2005 Jun 23;7(13):2731-4. doi: 10.1021/ol050901i.
[structure: see text] Analysis of the fermentation broth of a strain of the marine actinomycete Salinispora tropica has led to the isolation of two unprecedented macrolides, sporolides A (1) and B (2). The structures and absolute stereochemistries of both metabolites were elucidated using a combination of NMR spectroscopy and X-ray crystallography.
[结构：见正文] 对一株热带盐孢菌属海洋放线菌的发酵液进行分析，分离出了两种前所未有的大环内酯类化合物，即孢内酯A（1）和B（2）。利用核磁共振光谱和X射线晶体学相结合的方法阐明了这两种代谢产物的结构和绝对立体化学。
