Rivera-Sanfeliz Gerant, Kinney Thomas B, Rose Steven C, Agha Ayad K M, Valji Karim, Miller Franklin J, Roberts Anne C
Department of Radiology, UCSD Medical Center, 200 West Arbor Drive, San Diego, CA 92103, USA.
Cardiovasc Intervent Radiol. 2005 Sep-Oct;28(5):584-8. doi: 10.1007/s00270-004-0017-5.
To describe our experience with ultrasound (US)-guided percutaneous liver biopsies using the INRAD 18 G Express core needle biopsy system.
One hundred and fifty-four consecutive percutaneous core liver biopsy procedures were performed in 153 men in a single institution over 37 months. The medical charts, pathology reports, and radiology files were retrospectively reviewed. The number of needle passes, type of guidance, change in hematocrit level, and adequacy of specimens for histologic analysis were evaluated.
All biopsies were performed for histologic staging of chronic liver diseases. The majority of patients had hepatitis C (134/153, 90.2%). All patients were discharged to home after 4 hr of post-procedural observation. In 145 of 154 (94%) biopsies, a single needle pass was sufficient for diagnosis. US guidance was utilized in all but one of the procedures (153/154, 99.4%). The mean hematocrit decrease was 1.2% (44.1--42.9%). Pain requiring narcotic analgesia, the most frequent complication, occurred in 28 of 154 procedures (18.2%). No major complications occurred. The specimens were diagnostic in 152 of 154 procedures (98.7%).
Single-pass percutaneous US-guided liver biopsy with the INRAD 18 G Express core needle biopsy system is safe and provides definitive pathologic diagnosis of chronic liver disease. It can be performed on an outpatient basis. Routine post-biopsy monitoring of hematocrit level in stable, asymptomatic patients is probably not warranted.
描述我们使用INRAD 18G快速穿刺活检针系统进行超声（US）引导下经皮肝穿刺活检的经验。
在37个月内，于单一机构对153名男性连续进行了154例经皮肝穿刺活检。对病历、病理报告和放射学档案进行回顾性分析。评估穿刺针数、引导方式、血细胞比容水平变化以及组织学分析标本的充足性。
所有活检均用于慢性肝病的组织学分期。大多数患者为丙型肝炎（134/153，90.2%）。所有患者在术后观察4小时后均出院回家。154例活检中有145例（94%）单次穿刺即可确诊。除1例手术外（153/154，99.4%），其余均采用超声引导。血细胞比容平均下降1.2%（44.1--42.9%）。最常见的并发症是需要使用麻醉性镇痛药的疼痛，在154例手术中有28例（18.2%）发生。未发生重大并发症。154例手术中有152例（98.7%）标本具有诊断价值。
使用INRAD 18G快速穿刺活检针系统进行超声引导下单次经皮肝穿刺活检安全，可为慢性肝病提供明确的病理诊断。该操作可在门诊进行。对于稳定、无症状的患者，可能无需常规进行活检后血细胞比容水平监测。
