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双氯芬酸单剂量肌内注射用于减轻剖宫产术后疼痛:一项双盲随机对照试验

Diclofenac intramuscular single dose to decrease pain in post operative Caesarean section: a double blind randomized controlled trial.

作者信息

Bourlert Athicom

机构信息

Department of Obstetrics and Gynecology, Ranong Hospital, Ranong 85000, Thailand.

出版信息

J Med Assoc Thai. 2005 Jan;88(1):15-9.

Abstract

OBJECTIVE

To compare the use of diclofenac intramuscular single dose to decrease pain in post operative Caesarean section with none used.

STUDY DESIGN

A double blind randomized controlled trial.

SETTING

Department of Obstetrics and Gynecology, Ranong Hospital.

SUBJECTS

Sixty-four patients who underwent post operative Caesarean section in Ranong Hospital from October 2003 to March 2004.

INTERVENTION

The subjects were randomized by allocation to receive diclofenac intramuscular or placebo, both groups received morphine by Patient Controlled Analgesia (PCA).

MAIN OUTCOME MEASURES

Amount of morphine sulfate used, in both groups by Patient Controlled Analgesia (PCA) and level of pain using Visual Analog Score (VAscore).

RESULTS

Morphine was used significantly less in the group of patients who had diclofenac intramuscular single dose in post operative Caesarean section but the level of pain was not significantly different.

CONCLUSION

A single dose of diclofenac intramuscularly decreases the use of morphine during the in post operative period of Caesarean section.

摘要

目的

比较剖宫产术后单次肌内注射双氯芬酸与不使用该药减轻疼痛的效果。

研究设计

双盲随机对照试验。

研究地点

拉廊医院妇产科。

研究对象

2003年10月至2004年3月在拉廊医院接受剖宫产手术的64例患者。

干预措施

将研究对象随机分为两组,分别接受双氯芬酸肌内注射或安慰剂,两组均通过患者自控镇痛(PCA)使用吗啡。

主要观察指标

两组患者通过患者自控镇痛(PCA)使用硫酸吗啡的量以及使用视觉模拟评分(VAS评分)评估的疼痛程度。

结果

剖宫产术后单次肌内注射双氯芬酸的患者组使用吗啡的量显著减少,但疼痛程度无显著差异。

结论

剖宫产术后单次肌内注射双氯芬酸可减少术后吗啡的使用量。

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