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外耳道癌

Carcinoma of the external auditory canal.

作者信息

Isipradit Permsarp, Wadwongtham Winai, Aeumjaturapat Songklot, Aramwatanapong Phooripan

机构信息

Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.

出版信息

J Med Assoc Thai. 2005 Jan;88(1):114-7.

PMID:15960229
Abstract

Carcinoma of the external auditory canal is one of the most inaccessible areas of the body. It is a rare malignant neoplasm with an aggressive nature and an overall poor prognosis. In a ten year period, 16 patients were treated in King Chulalongkorn Memorial Hospital. From TNM staging proposed by the University of Pittsburgh, the authors found T1 = 1, T2 = 6, T3 = 5, T4 = 4 cases. In 14 patients who were operated on (radical mastoidectomy in 8, lateral temporal bone resection in 5, sleeve resection in 1), 7 had cured (50%), 7 were recurrence. 6 cases of recurrence developed in patients with radical mastoidectomy, 1 case with lateral temporal bone resection. The overall cure rate in stage I-II = 85.71% (6/7) but only 11.11% (1/9) in the advanced stages (III-IV). The present data suggest that in early cancer (stage I-II) the lateral temporal bone resection with postoperative radiation is better than radical mastoidectomy with postoperative radiation.

摘要

外耳道癌是人体最难触及的部位之一。它是一种罕见的恶性肿瘤,具有侵袭性,总体预后较差。在十年期间,朱拉隆功国王纪念医院共治疗了16例患者。根据匹兹堡大学提出的TNM分期,作者发现T1 = 1例,T2 = 6例,T3 = 5例,T4 = 4例。在14例接受手术的患者中(8例行根治性乳突切除术,5例行颞骨外侧切除术,1例行袖状切除术),7例治愈(50%),7例复发。6例复发发生在根治性乳突切除术患者中,1例发生在颞骨外侧切除术患者中。I-II期的总体治愈率为85.71%(6/7),但晚期(III-IV期)仅为11.11%(1/9)。目前的数据表明,对于早期癌症(I-II期),颞骨外侧切除术后放疗优于根治性乳突切除术后放疗。

相似文献

1
Carcinoma of the external auditory canal.外耳道癌
J Med Assoc Thai. 2005 Jan;88(1):114-7.
2
Treatments and outcomes of malignant tumors of external auditory canal.外耳道恶性肿瘤的治疗与预后
Am J Otolaryngol. 2009 Jan-Feb;30(1):44-8. doi: 10.1016/j.amjoto.2008.02.007. Epub 2008 Jul 22.
3
[The outcome of treatments for carcinoma of the external auditory canal].[外耳道癌的治疗结果]
Rev Laryngol Otol Rhinol (Bord). 2005;126(3):165-70.
4
Squamous cell carcinoma of the external auditory canal and middle ear: an operation combined with preoperative chemoradiotherapy and a free surgical margin.外耳道及中耳鳞状细胞癌:一种术前放化疗联合手术切缘阴性的手术方法
Otol Neurotol. 2006 Feb;27(2):242-8; discussion 249. doi: 10.1097/01.mao.0000190463.88873.3d.
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Squamous cell carcinoma of the temporal bone.颞骨鳞状细胞癌
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Cancer of the external auditory canal and middle ear in Denmark from 1992 to 2001.1992年至2001年丹麦外耳道和中耳癌情况
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Squamous cell carcinoma of the external auditory canal: long-term clinical outcomes using surgery and external-beam radiotherapy.外耳道鳞状细胞癌:手术联合外照射放疗的长期临床疗效
Am J Clin Oncol. 2009 Aug;32(4):401-4. doi: 10.1097/COC.0b013e31818f2d48.
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Squamous cell carcinoma of the external auditory canal: an evaluation of a staging system.外耳道鳞状细胞癌:一种分期系统的评估
Am J Otol. 2000 Jul;21(4):582-8.
9
[Cancer in the middle ear and the auditory canal].[中耳和耳道的癌症]
Ugeskr Laeger. 1995 Apr 10;157(15):2139-42.
10
Treatment and prognosis of squamous cell carcinoma of the external auditory canal and middle ear: a multi-institutional retrospective review of 87 patients.外耳道及中耳鳞状细胞癌的治疗与预后:87例患者的多机构回顾性研究
Int J Radiat Oncol Biol Phys. 2007 Aug 1;68(5):1326-34. doi: 10.1016/j.ijrobp.2007.01.052. Epub 2007 Apr 18.

引用本文的文献

1
Study of Clinicopathological Presentation and Management of Malignant Tumours of the Ear and Temporal Bone at Tertiary Care Cancer Hospital.三级护理癌症医院耳部及颞骨恶性肿瘤的临床病理表现及治疗研究
Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):3662-3670. doi: 10.1007/s12070-020-02346-2. Epub 2021 Jan 20.
2
Neoadjuvant chemotherapy in technically unresectable carcinoma of external auditory canal.外耳道技术上不可切除癌的新辅助化疗
Indian J Med Paediatr Oncol. 2015 Jul-Sep;36(3):172-5. doi: 10.4103/0971-5851.166734.
3
Rare case of temporal bone carcinoma with intracranial extension.
颞骨癌伴颅内扩展的罕见病例。
Indian J Otolaryngol Head Neck Surg. 2012 Dec;64(4):397-8. doi: 10.1007/s12070-011-0250-6. Epub 2011 May 21.
4
Lateral temporal bone resection for malignancy of external auditory meatus: our approach.外耳道恶性肿瘤的颞骨外侧切除术:我们的手术方法。
Indian J Otolaryngol Head Neck Surg. 2008 Sep;60(3):202-6. doi: 10.1007/s12070-008-0077-y. Epub 2008 Oct 22.
5
Squamous cell carcinoma of the external auditory canal.外耳道鳞状细胞癌。
Skull Base. 2008 May;18(3):167-72. doi: 10.1055/s-2007-994290.