Isipradit Permsarp, Wadwongtham Winai, Aeumjaturapat Songklot, Aramwatanapong Phooripan
Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
J Med Assoc Thai. 2005 Jan;88(1):114-7.
Carcinoma of the external auditory canal is one of the most inaccessible areas of the body. It is a rare malignant neoplasm with an aggressive nature and an overall poor prognosis. In a ten year period, 16 patients were treated in King Chulalongkorn Memorial Hospital. From TNM staging proposed by the University of Pittsburgh, the authors found T1 = 1, T2 = 6, T3 = 5, T4 = 4 cases. In 14 patients who were operated on (radical mastoidectomy in 8, lateral temporal bone resection in 5, sleeve resection in 1), 7 had cured (50%), 7 were recurrence. 6 cases of recurrence developed in patients with radical mastoidectomy, 1 case with lateral temporal bone resection. The overall cure rate in stage I-II = 85.71% (6/7) but only 11.11% (1/9) in the advanced stages (III-IV). The present data suggest that in early cancer (stage I-II) the lateral temporal bone resection with postoperative radiation is better than radical mastoidectomy with postoperative radiation.
外耳道癌是人体最难触及的部位之一。它是一种罕见的恶性肿瘤,具有侵袭性,总体预后较差。在十年期间,朱拉隆功国王纪念医院共治疗了16例患者。根据匹兹堡大学提出的TNM分期,作者发现T1 = 1例,T2 = 6例,T3 = 5例,T4 = 4例。在14例接受手术的患者中(8例行根治性乳突切除术,5例行颞骨外侧切除术,1例行袖状切除术),7例治愈(50%),7例复发。6例复发发生在根治性乳突切除术患者中,1例发生在颞骨外侧切除术患者中。I-II期的总体治愈率为85.71%(6/7),但晚期(III-IV期)仅为11.11%(1/9)。目前的数据表明,对于早期癌症(I-II期),颞骨外侧切除术后放疗优于根治性乳突切除术后放疗。