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依伴侬植入剂不良事件及停用情况的一年研究

One year study of Implanon on the adverse events and discontinuation.

作者信息

Chaovisitsaree Somsak, Piyamongkol Wirawit, Pongsatha Saipin, Morakote Nuntana, Noium Supranee, Soonthornlimsiri Nuchanart

机构信息

Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.

出版信息

J Med Assoc Thai. 2005 Mar;88(3):314-7.

Abstract

OBJECTIVE

To determine adverse events and discontinuation of Implanon in healthy Thai women between 16 and 45 years of age.

DESIGN

Prospective descriptive study.

SETTING

Family Planning Unit, Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University.

SUBJECTS

Ninety-two female volunteers with eligible criteria, no contraindication for hormonal contraceptive and wished to have long-term contraception were recruited.

MAIN OUTCOME MEASURES

Determination of adverse events was done three months after Implanon insertion. Discontinuation of Implanon use was reviewed during the study period of one year

RESULTS

Amenorrhea (40.2%) and infrequent bleeding (39.1%) were the most menstrual adverse events. While most non-menstrual adverse events were headache/dizziness (27.2%) and lower abdominal pain (23.9%). Severe non-menstrual side effect was rare (1-2%). Seven subjects (7.6%) discontinued using Implanon during the one year period of study.

CONCLUSION

Implanon demonstrated a high continue rate at the first year of insertion. It produced similar adverse events like other progestin-only contraceptives. Counseling before insertion is important for increased client satisfaction and a higher continuation rate.

摘要

目的

确定16至45岁健康泰国女性使用依伴侬(Implanon)的不良事件及停用情况。

设计

前瞻性描述性研究。

地点

清迈大学医学院妇产科计划生育科。

研究对象

招募了92名符合入选标准、无激素避孕禁忌且希望采用长效避孕方法的女性志愿者。

主要观察指标

在植入依伴侬三个月后确定不良事件。在为期一年的研究期间对依伴侬的停用情况进行评估。

结果

闭经(40.2%)和不规则出血(39.1%)是最常见的月经相关不良事件。而大多数非月经相关不良事件为头痛/头晕(27.2%)和下腹痛(23.9%)。严重的非月经相关副作用很少见(1 - 2%)。在一年的研究期间,有7名受试者(7.6%)停用了依伴侬。

结论

依伴侬在植入后的第一年显示出较高的持续使用率。它产生的不良事件与其他仅含孕激素的避孕药相似。植入前进行咨询对于提高客户满意度和持续使用率很重要。

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