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Acute tumor lysis syndrome triggered by zoledronic Acid in a patient with metastatic lung adenocarcinoma.

作者信息

Kurt Mevlut, Onal Ibrahim K, Elkiran Tamer, Altun Bulent, Altundag Kadri, Gullu Ibrahim

机构信息

Department of Internal Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey.

出版信息

Med Oncol. 2005;22(2):203-6. doi: 10.1385/MO:22:2:203.

DOI:10.1385/MO:22:2:203
PMID:15965285
Abstract

We report the case of a 52-yr-old man with metastatic lung adenocarcinoma who developed tumor lysis syndrome after administration of zoledronic acid. Tumor lysis syndrome in solid tumors and the antitumor effect of the zolendronic acid are discussed in light of the pertinent literature.

摘要

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本文引用的文献

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Zoledronic acid induces apoptosis and inhibits adhesion to mineralized matrix in prostate cancer cells via inhibition of protein prenylation.唑来膦酸通过抑制蛋白质异戊二烯化诱导前列腺癌细胞凋亡并抑制其与矿化基质的黏附。
BJU Int. 2004 Jul;94(1):164-70. doi: 10.1111/j.1464-4096.2004.04831.x.
2
Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: a randomized, Phase III, double-blind, placebo-controlled trial.唑来膦酸治疗非小细胞肺癌及其他实体瘤患者骨转移的长期疗效和安全性：一项随机、III期、双盲、安慰剂对照试验
Cancer. 2004 Jun 15;100(12):2613-21. doi: 10.1002/cncr.20308.
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唑来膦酸继发的严重多关节炎：一例报告及文献综述
Clin Cases Miner Bone Metab. 2015 Jan-Apr;12(1):69-74. doi: 10.11138/ccmbm/2015.12.1.069.
4
Tumor Lysis Syndrome in Solid Tumors: An up to Date Review of the Literature.实体瘤中的肿瘤溶解综合征：文献综述
Rare Tumors. 2014 Jun 13;6(2):5389. doi: 10.4081/rt.2014.5389. eCollection 2014 May 13.
5
Recognizing and managing the expanded risk of tumor lysis syndrome in hematologic and solid malignancies.识别和管理血液系统恶性肿瘤和实体瘤中肿瘤溶解综合征的扩大风险。
J Hematol Oncol. 2012 Dec 13;5:75. doi: 10.1186/1756-8722-5-75.
6
An unusual presentation of tumor lysis syndrome in a patient with advanced gastric adenocarcinoma: case report and literature review.晚期胃腺癌患者肿瘤溶解综合征的一种不寻常表现：病例报告及文献综述
Case Rep Med. 2012;2012:468452. doi: 10.1155/2012/468452. Epub 2012 May 27.
Antiproliferative efficacy of the third-generation bisphosphonate, zoledronic acid, combined with other anticancer drugs in leukemic cell lines.
第三代双膦酸盐唑来膦酸联合其他抗癌药物对白血病细胞系的抗增殖疗效。
Int J Hematol. 2004 Jan;79(1):37-43. doi: 10.1007/BF02983531.
4
The bisphosphonate zoledronic acid induces cytotoxicity in human myeloma cell lines with enhancing effects of dexamethasone and thalidomide.双膦酸盐唑来膦酸在人骨髓瘤细胞系中诱导细胞毒性，同时具有地塞米松和沙利度胺的增强作用。
Int J Hematol. 2003 Dec;78(5):443-9. doi: 10.1007/BF02983818.
5
Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro.唑来膦酸在体外对人胰腺癌细胞具有抗增殖和凋亡作用。
Br J Cancer. 2003 Jun 16;88(12):1971-8. doi: 10.1038/sj.bjc.6600986.
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Acute tumor lysis syndrome in solid tumors--a case report and review of the literature.实体瘤中的急性肿瘤溶解综合征——一例病例报告及文献综述
Cancer Chemother Pharmacol. 2003 Mar;51(3):187-92. doi: 10.1007/s00280-002-0556-x. Epub 2003 Feb 28.
7
Preclinical pharmacology of zoledronic acid.
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Am J Med Sci. 2003 Jan;325(1):38-40. doi: 10.1097/00000441-200301000-00008.
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