由三聚磷酸钙凝胶与尿素制得的含碳酸盐羟基磷灰石。

Carbonate-containing hydroxyapatite derived from calcium tripolyphosphate gel with urea.

作者信息

Mizutani Y, Hattori M, Okuyama M, Kasuga T, Nogami M

机构信息

R&D Center, NGK Spark Plug Co., Ltd., 2808 Iwasaki, Komaki, Aichi, 485-8510, Japan.

出版信息

J Mater Sci Mater Med. 2005 Aug;16(8):709-12. doi: 10.1007/s10856-005-2606-5.

DOI:10.1007/s10856-005-2606-5

PMID:15965739

Abstract

Carbonate containing hydroxyapatite (CO3HAp) is one of the candidate materials as a bioresorbable bone substitute. In the present work, CO3HAp was efficiently prepared by a hydrothermal treatment of calcium tripolyphosphate gel with urea at 140 degrees C for 24 h. Chemical potential plots of the CO3HAp for estimation of its dissolution behavior suggested that the CO3HAp is more soluble than hydroxyapatite (HAp) and is as soluble as octacalcium phosphate (OCP) and/or beta -tricalcium phosphate (TCP). This material is expected to be applied to bioresorbable materials such as bone fillers.

摘要

含碳酸羟基磷灰石（CO3HAp）是作为生物可吸收骨替代物的候选材料之一。在本研究中，通过在140℃下用尿素对三聚磷酸钙凝胶进行水热处理24小时，高效制备了CO3HAp。用于估计其溶解行为的CO3HAp的化学势图表明，CO3HAp比羟基磷灰石（HAp）更易溶解，并且与磷酸八钙（OCP）和/或β-磷酸三钙（TCP）的溶解性相同。这种材料有望应用于骨填充剂等生物可吸收材料。