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选择性栓塞术治疗难治性鼻出血。

Selective embolization in the treatment of intractable epistaxis.

作者信息

Andersen Pia Juul, Kjeldsen Anette Drøhse, Nepper-Rasmussen Jørgen

机构信息

Department of Otorhinolaryngology, Odense University Hospital, Odense, Denmark.

出版信息

Acta Otolaryngol. 2005 Mar;125(3):293-7. doi: 10.1080/00016480410023029.

DOI:10.1080/00016480410023029
PMID:15966700
Abstract

CONCLUSIONS

In skilled hands, selective embolization is a safe procedure and represents an effective treatment for prolonged epistaxis. Embolization therapy can be repeated if necessary.

OBJECTIVE

Severe posterior epistaxis is a common clinical problem in an ENT department and controlling the bleeding may present difficulties. Several methods are used to control posterior epistaxis, one of the latest treatment strategies being selective embolization of the nasal arteries. The aim of this study was to describe the effect of selective embolization in 22 patients treated with a total of 30 procedures at the ENT Department of Odense University Hospital between January 1995 and March 2004. To our knowledge this is the first Nordic work in which selective embolization has been used as a treatment strategy for patients with hereditary hemorrhagic telangiectasia (HHT).

MATERIAL AND METHODS

This was a retrospective review. Post-treatment effects and complications were evaluated by means of a questionnaire and a telephone interview. Owing to the different treatment strategies used, the results were evaluated for 2 groups of patients: Group A, 9 patients with HHT; and Group B, 13 patients with causes of epistaxis other than HHT.

RESULTS

In Group A, 15 procedures were performed, 12 of which were beneficial as the duration and number of episodes of epistaxis were reduced. In Group B, 15 procedures were performed and the success rate was 87%. One patient suffered from skin necrosis at the tip of the nose. No other serious side-effects of the treatment were observed.

摘要

结论

在技术熟练的医生手中,选择性栓塞是一种安全的操作,是治疗长期鼻出血的有效方法。如有必要,栓塞治疗可重复进行。

目的

严重的鼻后出血是耳鼻喉科常见的临床问题,控制出血可能存在困难。有多种方法用于控制鼻后出血,最新的治疗策略之一是选择性栓塞鼻动脉。本研究的目的是描述1995年1月至2004年3月在欧登塞大学医院耳鼻喉科对22例患者共进行30次操作的选择性栓塞效果。据我们所知,这是北欧首次将选择性栓塞用作遗传性出血性毛细血管扩张症(HHT)患者治疗策略的研究。

材料与方法

这是一项回顾性研究。通过问卷调查和电话访谈评估治疗后的效果和并发症。由于采用了不同的治疗策略,对两组患者的结果进行了评估:A组,9例HHT患者;B组,13例鼻出血病因非HHT的患者。

结果

A组进行了15次操作,其中12次有效,鼻出血的持续时间和发作次数减少。B组进行了15次操作,成功率为87%。1例患者鼻尖出现皮肤坏死。未观察到该治疗的其他严重副作用。

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