硅胶鼻腔拭子治疗遗传性出血性毛细血管扩张症的严重和难治性鼻出血：替代手术鼻孔闭合。
A silicone nasal swab for the treatment of severe and recalcitrant epistaxis in hereditary hemorrhagic telangiectasia: an alternative to surgical nostril closure.
机构信息
ENT Unit, Head and Neck Department, Azienda Ospedaliero-Universitaria Pisana, Via Paradisa 3, Pisa, Italy.
出版信息
Am J Otolaryngol. 2011 Jul-Aug;32(4):301-3. doi: 10.1016/j.amjoto.2010.06.003. Epub 2010 Aug 17.
BACKGROUND
Epistaxis is the most common symptom in patients with hereditary hemorrhagic telangiectasia (HHT). In severely affected cases, cessation of the nasal airflow seems to be the only long-term effective treatment. Such procedure deeply affects patient's quality of life (QoL) and is sometimes refused.
METHODS
This study investigated the effectiveness of a tailored silicone nasal swab on 2 patients affected by HHT and severe epistaxis.
RESULTS
In both cases, we observed a good clinical effect, with significant reduction of epistaxis and improved QoL.
CONCLUSIONS
Our preliminary results indicate that the silicone nasal swab can be considered an effective way of treating severe epistaxis in patients with HHT. Its advantages, in terms of maintained airflow patency, reversibility, and improved QoL, are highlighted.
背景
鼻出血是遗传性出血性毛细血管扩张症（HHT）患者最常见的症状。在病情严重的情况下，停止鼻气流似乎是唯一长期有效的治疗方法。这种方法会严重影响患者的生活质量（QoL），有时会被拒绝。
方法
本研究调查了定制硅胶鼻拭子对 2 例 HHT 伴严重鼻出血患者的疗效。
结果
在这两种情况下，我们观察到了良好的临床效果，明显减少了鼻出血并改善了生活质量。
结论
我们的初步结果表明，硅胶鼻拭子可以被认为是治疗 HHT 患者严重鼻出血的一种有效方法。它具有保持气流通畅、可逆转和改善生活质量等优点。
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