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造影剂:与其他药物的相互作用及临床试验

Contrast media: interactions with other drugs and clinical tests.

作者信息

Morcos Sameh K, Thomsen Henrik S, Exley C M

机构信息

Department of Diagnostic Imaging, Northern General Hospital, Sheffield Teaching Hospitals NHS Trust, UK.

出版信息

Eur Radiol. 2005 Jul;15(7):1463-8. doi: 10.1007/s00330-004-2600-1. Epub 2005 Jan 26.

DOI:10.1007/s00330-004-2600-1
PMID:15968520
Abstract

Many patients with multiple medical problems who are receiving a variety of drugs are investigated with imaging techniques which require intravascular contrast media. The Contrast Media Safety Committee of the European Society of Urogenital Radiology therefore decided to review the literature and to draw up simple guidelines on interactions between contrast media and other drugs. An extensive literature search was carried out and summarized in a report. Based on the available information, simple guidelines have been drawn up. The report and guidelines were discussed at the 11th European Symposium on Urogenital Radiology in Santiago de Compostela. Contrast media may interact with other drugs, and may interfere with isotope studies and biochemical measurements. Awareness of the patient drug history is important to avoid potential hazards. Simple guidelines are presented.

摘要

许多患有多种疾病且正在服用多种药物的患者会接受需要血管内造影剂的成像检查。因此,欧洲泌尿生殖放射学会造影剂安全委员会决定回顾相关文献,并制定关于造影剂与其他药物相互作用的简单指南。开展了广泛的文献检索并汇总成一份报告。基于现有信息,已制定了简单指南。该报告和指南在圣地亚哥德孔波斯特拉举行的第11届欧洲泌尿生殖放射学研讨会上进行了讨论。造影剂可能与其他药物相互作用,并可能干扰同位素研究和生化测量。了解患者的用药史对于避免潜在危害很重要。现给出简单指南。

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本文引用的文献

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Safety of ultrasound contrast agents.超声造影剂的安全性。
Eur Radiol. 2005 May;15(5):941-5. doi: 10.1007/s00330-004-2601-0. Epub 2005 Jan 21.
2
Effect of iodinated contrast media on thyroid function in adults.碘化造影剂对成人甲状腺功能的影响。
Eur Radiol. 2004 May;14(5):902-7. doi: 10.1007/s00330-004-2238-z. Epub 2004 Feb 28.
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Gadolinium magnetic resonance contrast agents produce analytic interference in multiple serum assays.钆磁共振造影剂在多种血清检测中会产生分析干扰。
Biol Trace Elem Res. 2019 Jun;189(2):426-436. doi: 10.1007/s12011-018-1496-6. Epub 2018 Sep 13.
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Analytical Interference by Contrast Agents in Biochemical Assays.分析干扰物在生化分析中的应用。
Contrast Media Mol Imaging. 2017 Apr 10;2017:1323802. doi: 10.1155/2017/1323802. eCollection 2017.
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Outcome Differences between Intra-Arterial Iso- and Low-Osmolality Iodinated Radiographic Contrast Media in the Interventional Management of Stroke III Trial.动脉内等渗与低渗碘化造影剂在卒中介入治疗III期试验中的疗效差异
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Eur Radiol. 2006 May;16(5):1041-9. doi: 10.1007/s00330-005-0081-5. Epub 2006 Jan 5.
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Eur Radiol. 2006 May;16(5):1050-3. doi: 10.1007/s00330-005-0064-6. Epub 2005 Dec 13.
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Gadodiamide administration causes spurious hypocalcemia.钆双胺给药会导致假性低钙血症。
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Contrast-media-induced nephrotoxicity: a consensus report. Contrast Media Safety Committee, European Society of Urogenital Radiology (ESUR).对比剂诱导的肾毒性:一份共识报告。对比剂安全委员会,欧洲泌尿生殖放射学会(ESUR)。
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