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轻度创伤性脑损伤的神经心理学研究:1995年以来研究的荟萃分析综述

Neuropsychological studies of mild traumatic brain injury: a meta-analytic review of research since 1995.

作者信息

Frencham Katherine A R, Fox Allison M, Maybery Murray T

机构信息

School of Psychology, University of Western Australia, Crawley, Australia.

出版信息

J Clin Exp Neuropsychol. 2005 Apr;27(3):334-51. doi: 10.1080/13803390490520328.

Abstract

A meta-analysis conducted by Binder, Rohling and Larrabee established a relationship between mild traumatic brain injury (TBI) and small reductions in cognitive functioning in individuals assessed more than 3 months post-injury. As a follow-up, this study summarized similar research that (1) was published since the previous meta-analysis, and (2) included data collected at any stage post-injury. An extensive literature search revealed 17 suitable studies from which effect sizes were aggregated. The overall effect size was g = 0.32, p < .001. Speed of processing measures had the largest effect, g = 0.47, p < .001. The merging of post-acute effect sizes with those reported in Binder et al.'s review yielded a nonsignificant result, g = 0.11. Time since injury was found to be a significant moderator variable, with effect sizes tending to zero with increasing time post injury.

摘要

Binder、Rohling和Larrabee进行的一项荟萃分析确定了轻度创伤性脑损伤(TBI)与受伤后3个月以上接受评估的个体认知功能的小幅下降之间的关系。作为后续研究,本研究总结了类似的研究,这些研究(1)自上次荟萃分析以来发表,(2)包括在受伤后任何阶段收集的数据。广泛的文献检索发现了17项合适的研究,并对效应量进行了汇总。总体效应量为g = 0.32,p < .001。处理速度测量的效应最大,g = 0.47,p < .001。急性后期效应量与Binder等人综述中报告的效应量合并后,结果不显著,g = 0.11。发现受伤后的时间是一个显著的调节变量,随着受伤后时间的增加,效应量趋于零。

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