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[新生儿缺氧缺血性脑病时脑室周围坏死及脑内轻度病理形态学改变的分布]

[Distribution of periventricular necrosis and mild pathomorphologic changes in the brain in hypoxic-ischemic encephalopathy in neonates].

作者信息

Dvorák K

机构信息

II. patologicko-anatomický ústav Lékarské fakulty, Masarykovy univerzity, Brno.

出版信息

Cesk Patol. 1992 Mar;28(1):3-8.

PMID:1596942
Abstract

An analysis of histotopographic sections from 31 neonatal brains with hypoxic periventricular necroses. Distribution and topography of necroses was traced in 7 frontal planes in correlation to frequency of impaired white matter tracts. Results were summarized in schemes. Another topic of analysis was morphology of a slight white matter impairment (spongiosis). Used three grade classification of slight white matter impairment contributed to morphologic criteria of neonatal hypoxic-ischemic encephalopathy. Having considered his own findings and data from literature the author decided a standard histological tissue sampling for perinatal encephalopathies.

摘要

对31例患有缺氧性脑室周围坏死的新生儿大脑组织切片进行组织拓扑学分析。追踪7个额面坏死灶的分布和拓扑结构,并与白质束受损频率相关联。结果以图表形式总结。另一个分析主题是轻度白质损伤(海绵样变)的形态学。采用的轻度白质损伤三级分类法有助于新生儿缺氧缺血性脑病的形态学标准制定。作者综合自己的研究结果和文献数据,确定了围产期脑病的标准组织学取材方法。

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