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[手术样本中的肝硬化]

[Liver cirrhosis in surgical samples].

作者信息

Lauko L

机构信息

Ustav patologickej anatómie LF UK a FNsP, Martin.

出版信息

Cesk Patol. 1992 Mar;28(1):57-63.

PMID:1596946
Abstract

1729 liver excisions from patients with laparotomy (1302 women, 427 men) were analyzed during 5 years (1984-1988). There were 12 cirrhoses among them (in 6 women and 6 men) with medium history of about 5 years. HBsAg was proved both according to Shikata and immunohistochemically in 4 cirrhoses, two of them were serologically positive, only one known before operation. A case of seroconversion was observed (repeated seronegativity with histochemical and immunochemical HBsAg positivity). Men: women ratio of 3:1 correlated with the literature as well as the prevalence of macronodular and mixed cirrhosis in women and micronodular cirrhosis in men. Paper points out an infection risk in surgical staff operating on cases with unrevealed HBsAg positivity.

摘要

在5年(1984 - 1988年)期间,对1729例接受剖腹手术患者(1302名女性,427名男性)的肝脏切除术进行了分析。其中有12例肝硬化患者(6名女性和6名男性),平均病程约5年。根据Shikata法和免疫组织化学方法,在4例肝硬化患者中证实存在HBsAg,其中2例血清学阳性,术前仅知1例。观察到1例血清学转换(组织化学和免疫化学HBsAg阳性但血清学反复阴性)。男女比例为3:1,与文献报道以及女性大结节性和混合性肝硬化、男性小结节性肝硬化的患病率相符。本文指出,在对未发现HBsAg阳性的病例进行手术的外科工作人员中存在感染风险。

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