Duncan P G, Cohen M M, Tweed W A, Biehl D, Pope W D, Merchant R N, DeBoer D
Department of Anesthesia, University of Saskatchewan, Canada.
Can J Anaesth. 1992 May;39(5 Pt 1):440-8. doi: 10.1007/BF03008707.
To understand better the factors important to the safety of anaesthesia provided for day surgical procedures, we analyzed the intraoperative and immediate postoperative course of patients at four Canadian teaching hospitals' day treatment centres. After excluding those who received only monitored anaesthesia care, there were 6,914 adult (non-obstetrical) patients seen over a twelve-month period in 1988-89. The rate of adverse outcome consequent to their care was identified by a comprehensive surveillance system which included review of anaesthetic records (four hospitals) and follow-up telephone calls (two hospitals). The relationship between adverse events and preoperative factors was determined by using a multiple logistic regression analysis that included age, sex, duration of the procedure and the hospital care. There were no deaths during the study period and major morbid events were infrequent. Patient preoperative disease was predictive of some intraoperative events relating to the same organ system, but not to events in the PACU. Some unexpected relationships emerged including preoperative hypertension being related to a greater risk of difficult intubation, and neurological disease to perioperative cardiac abnormalities. Patients judged obese, or inadequately fasted, were found to experience a greater rate of recovery problems as well as discomfort. While the low response rate (36%) to the telephone interviews created a sampling bias, the high rate of patient dissatisfaction among those reached is disconcerting. We conclude that day surgical patients with preoperative medical conditions, even when optimally managed, are at higher risk for adverse events in the perioperative period.
为了更好地了解日间手术麻醉安全的重要因素,我们分析了加拿大四家教学医院日间治疗中心患者的术中及术后即刻情况。在排除仅接受监护麻醉护理的患者后,1988 - 1989年的十二个月期间共观察了6914例成年(非产科)患者。通过一个综合监测系统确定了因他们的护理导致的不良后果发生率,该系统包括对麻醉记录的审查(四家医院)和随访电话(两家医院)。使用多元逻辑回归分析确定不良事件与术前因素之间的关系,该分析包括年龄、性别、手术持续时间和医院护理情况。研究期间无死亡病例,严重不良事件也很少见。患者术前疾病可预测一些与同一器官系统相关的术中事件,但不能预测麻醉后恢复室(PACU)中的事件。出现了一些意外关系,包括术前高血压与插管困难风险增加有关,以及神经疾病与围手术期心脏异常有关。被判定为肥胖或禁食不充分的患者恢复问题发生率更高,不适也更多。虽然电话访谈的低回复率(36%)造成了抽样偏差,但受访患者中较高的不满率令人不安。我们得出结论,即使得到最佳管理,有术前医疗状况的日间手术患者在围手术期发生不良事件的风险更高。