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木腿之谜:东非监狱中的维生素C缺乏症

The mystery of the wooden leg: vitamin C deficiency in East African prisons.

作者信息

Bennett M, Coninx R

机构信息

International Committee of the Red Cross, 19 Avenue de la Paix, CH-1202-Geneva, Switzerland.

出版信息

Trop Doct. 2005 Apr;35(2):81-4. doi: 10.1258/0049475054036896.

Abstract

Vitamin C deficiency (scurvy) is an uncommon disease in modern times, and therefore easily misdiagnosed when it appears. While visiting prisoners in East Africa, health delegates of the International Committee of the Red Cross (ICRC) encountered prisoners suffering from a hitherto undiagnosed 'mysterious' illness, consisting mainly of swollen and hard legs, that had not responded to various treatments given by the local health centre or hospital. The ICRC set out to investigate the nature of this disease and examined 133 prisoners with the suspected clinical symptoms described as 'wooden leg' syndrome in 10 different prisons. Serum ascorbic acid levels were measured and a food basket analysis done. The diagnosis of scurvy was confirmed. All patients responded to standard treatment with oral ascorbic acid. The clinical presentation of scurvy in these East African prisons seems to be somewhat different from the classic descriptions, but is in line with historic records of the disease. Treatment is easy and cheap, and response to treatment is quick. Scurvy remains a problem in prisons in Africa and clinicians working in prisons need to be aware of its presence and its presentations.

摘要

维生素C缺乏症(坏血病)在现代是一种罕见疾病,因此发病时很容易被误诊。红十字国际委员会(ICRC)的健康代表在探访东非的囚犯时,遇到了一些患有一种此前未被诊断出的“神秘”疾病的囚犯,主要症状是腿部肿胀、发硬,当地卫生中心或医院给予的各种治疗均不见效。ICRC着手调查这种疾病的性质,并对10所不同监狱中133名有疑似临床症状(被描述为“木腿”综合征)的囚犯进行了检查。测量了血清抗坏血酸水平并进行了食物篮分析。坏血病的诊断得到了证实。所有患者对口服抗坏血酸的标准治疗均有反应。这些东非监狱中坏血病的临床表现似乎与经典描述有所不同,但与该疾病的历史记录相符。治疗简单且费用低廉,对治疗的反应迅速。坏血病在非洲监狱中仍然是一个问题,在监狱工作的临床医生需要意识到它的存在及其表现形式。

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