Kurella Anil, Dahotre Narendra B
Department of Materials Science and Engineering, The University of Tennessee, Knoxville, 37996, USA.
J Biomater Appl. 2005 Jul;20(1):5-50. doi: 10.1177/0885328205052974.
Often hard implants undergo detachment from the host tissue due to inadequate biocompatibility and poor osteointegration. Changing surface chemistry and physical topography of the surface influences biocompatibility. At present, the understanding of biocompatibility of both virgin and modified surfaces of bioimplant materials is limited and a great deal of research is being dedicated to this aspect. In view of this, the current review casts new light on research related to the surface modification of biomaterials, especially materials for prosthetic applications. A brief overview of the major surface modification techniques has been presented, followed by an in-depth discussion on laser surface modifications that have been explored so far along with those that hold tremendous potential for bioimplant applications.
通常情况下,硬质植入物会因生物相容性不足和骨整合不良而与宿主组织分离。改变材料表面的化学性质和物理形貌会影响生物相容性。目前,对于生物植入材料原始表面和改性表面的生物相容性的理解都很有限,大量研究正致力于这方面。鉴于此,本综述为生物材料表面改性相关研究,尤其是假体应用材料的研究带来了新的启示。文中简要概述了主要的表面改性技术,随后深入讨论了迄今为止已探索的激光表面改性以及那些在生物植入应用中具有巨大潜力的激光表面改性。