Shcherbakov V P
Zh Obshch Biol. 2005 May-Jun;66(3):195-211.
The idea is discussed that the common output of any evolution is creation of the entities that are increasingly resistant to further evolution. The moving force of evolution is entropy, the tendency to disorder. This general aspiration for chaos is a cause of the mortality of organisms and species, however, being prerequisite for any movement, it creates (by chance) novelties, which may occur (by chance) more resistant to further decay and thus survive. The surviving of those who survive is the most general principle of evolution discovered by Darwin for particular case of biological evolution. The second law of thermodynamics states that our Universe is perishing but its ontology is such that it creates resistance to destruction. The evolution is a history of this resistance. Not only those who die do not survive but also those who evolve. The entities that change (evolve) rapidly disappear rapidly and by this reason they are not observed among both the fossils and now-living organisms. We know only about long-living species. All the existing organisms are endowed with an ability to resist other changing. The following main achievements of the species homeostasis are discussed: high fidelity of DNA replication and effective mechanisms of DNA repair; diploidy; normalizing selection; truncated selection; heterozygote superiority; ability to change phenotype adaptively without changing genotype; parental care and the K-strategy of reproduction; behavior that provides independence of the environment. The global resistance of the living systems to entropy is provided the state that all the essential in biology is determined not by physical-chemical interactions but could semantic rules. A conception of "potential zygotic information" that determines the rules of ontogenesis is proposed. A zygote does not contain this information in explicit form. It is created de novo step by step during ontogenesis and it could not be decoded beforehand. The experimental data on the adaptive mutagenesis and the relevant hypothesis are discussed. It is concluded that the special mechanisms for speeding-up of evolution as created by evolution are impossible conceptually.
本文探讨了一种观点,即任何进化的共同结果都是创造出对进一步进化具有更强抵抗力的实体。进化的驱动力是熵,即走向无序的趋势。这种对混乱的普遍渴望是生物体和物种死亡的原因,然而,作为任何运动的先决条件,它(偶然地)创造出新奇事物,这些新奇事物可能(偶然地)对进一步的衰败更具抵抗力,从而得以存活。那些幸存者的生存是达尔文在生物进化的特定案例中发现的最普遍的进化原则。热力学第二定律表明,我们的宇宙正在走向灭亡,但其本体论是这样的,即它创造出对毁灭的抵抗力。进化就是这种抵抗力的历史。不仅那些死亡的个体无法存活,那些进化的个体也同样如此。快速变化(进化)的实体迅速消失,正因如此,在化石和现存生物中都观察不到它们。我们只了解长寿的物种。所有现存的生物体都具备抵抗其他变化的能力。文中讨论了物种稳态的以下主要成就:DNA复制的高保真度和有效的DNA修复机制;二倍体;正态化选择;截短选择;杂合优势;在不改变基因型的情况下适应性改变表型的能力;亲代抚育和K型繁殖策略;提供对环境独立性的行为。生命系统对熵的全局抵抗力是由这样一种状态提供的,即生物学中所有的本质不是由物理化学相互作用决定的,而是由语义规则决定的。提出了一种决定个体发育规则的“潜在合子信息”概念。合子并不以明确的形式包含这种信息。它在个体发育过程中逐步从头创建,并且无法预先解码。文中讨论了适应性诱变的实验数据及相关假说。得出的结论是,进化所创造的加速进化的特殊机制在概念上是不可能的。