Azad Raj Vardhan, Lakshminarayana Pasumala, Kumar Harsh, Talwar Dinesh, Pal Nikhil, Chandra Parijat
Vitreo-Retina Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
J Pediatr Ophthalmol Strabismus. 2005 May-Jun;42(3):149-54. doi: 10.3928/01913913-20050501-02.
To study the ocular growth pattern in cryotherapy- and laser-treated prethreshold retinopathy of prematurity (ROP) and its effect on scleral rigidity.
In a prospective study, axial length, anterior chamber depth, and scleral rigidity were assessed in 12 eyes with no ROP, 12 eyes with spontaneously regressed ROP, 12 eyes with cryotherapy-treated prethreshold ROP, and 14 eyes with diode laser-treated prethreshold ROP at 36 weeks, 40 weeks, and 52 weeks postconceptional age.
Cryotherapy- and laser-treated ROP eyes at prethreshold stage exhibited shorter axial lengths and shallower anterior chamber depth compared to eyes with no ROP or spontaneously regressed ROP. Scleral rigidity was not altered in ROP eyes including those that underwent cryotherapy or laser treatment.
Growth of eyes with ROP is arrested including those treated with cryotherapy or laser at prethreshold stage. Cryotherapy or laser treatment has no weakening effect on the scleral coat.
研究冷冻疗法和激光治疗阈值前早产儿视网膜病变（ROP）的眼生长模式及其对巩膜硬度的影响。
在一项前瞻性研究中，对12只无ROP的眼、12只ROP自然消退的眼、12只冷冻疗法治疗阈值前ROP的眼和14只二极管激光治疗阈值前ROP的眼，在孕龄36周、40周和52周时评估眼轴长度、前房深度和巩膜硬度。
与无ROP或ROP自然消退的眼相比，阈值前阶段接受冷冻疗法和激光治疗的ROP眼眼轴长度较短，前房深度较浅。包括接受冷冻疗法或激光治疗的ROP眼在内，其巩膜硬度未改变。
ROP眼的生长停滞，包括阈值前阶段接受冷冻疗法或激光治疗的眼。冷冻疗法或激光治疗对巩膜没有削弱作用。
