Mackey Richard A, Brody Fredrick J, Berber Eren, Chand Bipan, Henderson J Michael
Department of General Surgery, The Cleveland Clinic Foundation, Cleveland, OH, USA.
J Am Coll Surg. 2005 Jul;201(1):71-6. doi: 10.1016/j.jamcollsurg.2005.01.025.
Subxiphoid hernias are difficult to repair. This study attempts to identify risk factors associated with incisional hernia formation after median sternotomy.
A retrospective review was conducted on patients undergoing subxiphoid incisional hernia repair between 1995 and 2002. The study group was compared with a group undergoing similar cardiothoracic procedures as to body mass index (BMI), comorbidities, complications, tobacco use, length of stay, ICU stay, bypass time, transfusion requirements, and wound infections. Statistical analysis utilized Student's t-test, chi-square, and Kaplan-Meier analysis.
A total of 117 subxiphoid hernias were repaired; 45 were used for comparison with a matched cohort of 79 patients. Average time between sternotomy and hernia repair was 24.3 months (+/-16.8) with 22 (49%) patients developing hernias within 2 years. Mean followup was 48 months. The study group differed significantly from the nonhernia group in age (56.6 +/- 13.0 versus 62.2 +/- 8.9, p = 0.01), mean length of stay (16.3 +/- 22.8 versus 10.2 +/- 6.7, p = 0.03), BMI (29.6 +/- 4.5 versus 27.2 +/- 4.5, p = 0.01), number of transplantation patients (10 versus 1, p = 0.0003), and presence of sternal wound infection (18% versus 3.9%, p = 0.02). Multivariate analysis revealed significance in regard to transfusion requirements (p = 0.015) and approached statistical significance with BMI (p = 0.058). Of the 45 patients undergoing hernia repair, 31(69%) had a mesh repair and 10 (32%) patients recurred. Six (43%) patients without a mesh repair recurred. Seventy-five percent of the patients with sternal wound infections developed recurrent hernias.
Transfusion requirements, BMI, and sternal wound infections might be associated with subxiphoid hernias after median sternotomy. Sternal wound infection increases the risk of recurrent incisional hernia.
剑突下疝修补困难。本研究旨在确定正中胸骨切开术后与切口疝形成相关的危险因素。
对1995年至2002年间接受剑突下切口疝修补术的患者进行回顾性研究。将研究组与接受类似心胸手术的一组患者在体重指数(BMI)、合并症、并发症、吸烟情况、住院时间、重症监护病房(ICU)住院时间、体外循环时间、输血需求及伤口感染方面进行比较。统计分析采用学生t检验、卡方检验和Kaplan-Meier分析。
共修补117例剑突下疝;45例用于与79例匹配队列患者进行比较。胸骨切开术至疝修补的平均时间为24.3个月(±16.8),22例(49%)患者在2年内发生疝。平均随访48个月。研究组与无疝组在年龄(56.6±13.0对62.2±8.9,p = 0.01)、平均住院时间(16.3±22.8对10.2±6.7,p = 0.03)、BMI(29.6±4.5对27.2±4.5,p = 0.01)、移植患者数量(10对1,p = 0.0003)及胸骨伤口感染情况(18%对3.9%,p = 0.02)方面存在显著差异。多因素分析显示输血需求具有显著意义(p = 0.015),BMI接近统计学意义(p = 0.058)。在45例接受疝修补的患者中,31例(69%)采用补片修补,10例(32%)复发。6例(43%)未采用补片修补的患者复发。75%有胸骨伤口感染的患者发生复发性疝。
输血需求、BMI和胸骨伤口感染可能与正中胸骨切开术后剑突下疝有关。胸骨伤口感染会增加切口疝复发的风险。