Nagashima Fumihiro, Kishi Katsuhiro, Hamada Yuko, Takaoka Shigeru, Asakawa Yoshinori
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-Cho, Tokushima 770-8514, Japan.
Phytochemistry. 2005 Jul;66(14):1662-70. doi: 10.1016/j.phytochem.2005.05.012.
Three ent-verticillane diterpenoids and two ent-sesquiterpenoids were isolated from the Japanese liverwort Jackiella javanica Schiffn. together with five known ent-verticillane and three ent-kaurane diterpenoids, and three sesquiterpenoids. Five ent-verticillane epoxides were synthetically prepared from ent-verticillols action to clarify the absolute configuration of natural ent-9,10-epoxyverticillol. Their structures were established by extensive NMR spectroscopic and X-ray crystallographic analyses.
从日本苔类植物爪哇拟复叉苔（Jackiella javanica Schiffn.）中分离出3个对映-维蒂希兰二萜和2个对映-倍半萜，以及5个已知的对映-维蒂希兰二萜、3个对映-贝壳杉烷二萜和3个倍半萜。通过对映-维蒂希醇的反应合成制备了5个对映-维蒂希兰环氧化物，以阐明天然对映-9,10-环氧维蒂希醇的绝对构型。通过广泛的核磁共振光谱和X射线晶体学分析确定了它们的结构。
