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化疗期间颅内结核瘤的反常扩大。

Paradoxical expansion of intracranial tuberculomas during chemotherapy.

作者信息

Chambers S T, Hendrickse W A, Record C, Rudge P, Smith H

出版信息

Lancet. 1984 Jul 28;2(8396):181-4. doi: 10.1016/s0140-6736(84)90478-1.

DOI:10.1016/s0140-6736(84)90478-1
PMID:6146749
Abstract

4 patients with tuberculosis, 3 of whom had tuberculous meningitis, were noted to have tuberculomas on computed tomographic scanning. During antituberculous chemotherapy the intracranial lesions increased in size in all 4 patients at a time when the clinical state and cerebrospinal-fluid abnormalities were improving; in 2 of the patients the regional lymph nodes also enlarged greatly. Though the expansion of the cerebral lesions caused anxiety and led to some changes in chemotherapy, the lesions eventually diminished in size.

摘要

4例肺结核患者,其中3例患有结核性脑膜炎,经计算机断层扫描发现有结核瘤。在抗结核化疗期间,所有4例患者的颅内病变在临床状态和脑脊液异常情况正在改善时却增大;其中2例患者的局部淋巴结也明显肿大。尽管脑部病变的扩大引起焦虑并导致化疗方案有所改变,但病变最终还是缩小了。

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Paradoxical expansion of intracranial tuberculomas during chemotherapy.化疗期间颅内结核瘤的反常扩大。
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