Bhargava S, Gupta A K, Tandon P N
Br J Radiol. 1982 Mar;55(651):189-96. doi: 10.1259/0007-1285-55-651-189.
This study comprises 60 cases of tuberculous meningitis including both adults and children. Only three cases showed a normal scan. Severe hydrocephalus was present in 87.09% children and only 12.09% adults. The incidence of hydrocephalus increased with the duration of the illness and decreased with age. Exudates in the basal cisterns were graded from mild to severe, the latter being seen only in children. Visible infarcts were shown in 28.33% of cases, 10% showed associated parenchymal tuberculomas. Serial follow-up scans indicate that patients with non-enhancing exudates have a good prognosis when medically treated, whereas in those cases with enhancing exudates the prognosis is poor in spite of medical treatment and surgical shunting; they either succumb to their illness or are left with irreversible sequelae. CT has proved sensitive in both the diagnosis and prognosis in clinically suspected tuberculous meningitis.
本研究包括60例结核性脑膜炎病例,涵盖成人和儿童。仅3例扫描结果正常。87.09%的儿童存在严重脑积水,而成人中仅有12.09%。脑积水的发生率随病程延长而增加,随年龄增长而降低。基底池渗出物从轻度到重度分级,后者仅见于儿童。28.33%的病例可见梗死灶,10%伴有实质结核瘤。系列随访扫描表明,非强化渗出物患者经药物治疗预后良好,而强化渗出物患者尽管接受了药物治疗和手术分流,预后仍较差;他们要么因病死亡,要么留下不可逆的后遗症。CT已被证明在临床疑似结核性脑膜炎的诊断和预后判断中均具有敏感性。