Houck Philip D, Lethen Jan E, Riggs Mark W, Gantt D Scott, Dehmer Gregory J
Department of Medicine, Division of Cardiology, The Scott & White Hospital and Clinic, Temple, Texas, USA.
Am J Cardiol. 2005 Jul 1;96(1):45-51. doi: 10.1016/j.amjcard.2005.02.042.
Previous studies have demonstrated variation in vascular events with respect to season and time of day. Changes in barometric pressure display daily and seasonal variations and could modulate the occurrence of vascular events. The objective of this study was to determine whether a relation exists between changes in barometric pressure and occurrence of stroke or acute myocardial infarction (AMI). A retrospective analysis of hospital admissions for AMI and stroke from 1993 to 1996 in central Texas was related to changes in atmospheric pressure that were obtained from the National Climatic Data Center. Patients who had AMI (n = 1,327) or stroke (n = 839) were identified from a computerized hospital database. Mean atmospheric pressure, greatest change in pressure, and rate of change in pressure per 24-hour period were computed. One-, 2-, and 3-day and seasonal groupings of cardiovascular events were related to corresponding changes in barometric pressure. The fall and winter seasons had the highest variability in atmospheric pressure readings. There was a significant correlation (p = 0.0083) between a decrease in atmospheric pressure and the occurrence of AMI the day after a pressure decrease, especially during the fall and winter seasons. No relation between stroke and atmospheric pressure was demonstrated. In conclusion, we conclude that rapid decreases in barometric pressure are associated with the occurrence of AMI but not of stroke.
以往的研究已经证明，血管事件在季节和一天中的时间方面存在差异。气压变化呈现出每日和季节性变化，并且可能调节血管事件的发生。本研究的目的是确定气压变化与中风或急性心肌梗死（AMI）的发生之间是否存在关联。对1993年至1996年德克萨斯州中部地区因AMI和中风而住院的病例进行回顾性分析，并将其与从国家气候数据中心获取的大气压力变化相关联。从计算机化的医院数据库中识别出患有AMI（n = 1327）或中风（n = 839）的患者。计算平均大气压力、压力的最大变化以及每24小时的压力变化率。将心血管事件的1天、2天和3天以及季节性分组与气压的相应变化相关联。秋冬季节的大气压力读数变化最大。气压下降与气压下降后第二天AMI的发生之间存在显著相关性（p = 0.0083），尤其是在秋冬季节。未证明中风与大气压力之间存在关联。总之，我们得出结论，气压的快速下降与AMI的发生相关，但与中风的发生无关。
