Association of deranged adrenal steroid metabolism with anemia in chronic heart failure.

作者信息

Okonko Darlington O, Crosato Martino, Kalra Paul R, Cicoira Mariantonietta, John Matthias, Doehner Wolfram, Coats Andrew J S, Poole-Wilson Philip A, Anker Stefan D

机构信息

Clinical Cardiology, National Heart and Lung Institute, Imperial College, London, UK.

出版信息

Am J Cardiol. 2005 Jul 1;96(1):101-3. doi: 10.1016/j.amjcard.2005.02.053.

DOI:10.1016/j.amjcard.2005.02.053

PMID:15979444

Abstract

The relation between adrenal steroid hormone imbalance, as quantified by the cortisol/dehydroepiandrosterone (DHEA) ratio, and hemoglobin concentrations was appraised in 92 men with stable chronic heart failure (CHF). The cortisol/DHEA ratio was independently and inversely associated with hemoglobin concentrations, suggesting that alterations of the steroid milieu may play a role in the pathogenesis of anemia in CHF.

摘要