SCANMOT：通过同时扫描多个序列基序来搜索相似序列。
SCANMOT: searching for similar sequences using a simultaneous scan of multiple sequence motifs.
作者信息
Chakrabarti Saikat, Anand A Prem, Bhardwaj Nitin, Pugalenthi Ganesan, Sowdhamini R
机构信息
National Centre for Biological Sciences (NCBS), Bangalore 560065, India.
出版信息
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W274-6. doi: 10.1093/nar/gki493.
Abstract
Establishment of similarities between proteins is very important for the study of the relationship between sequence, structure and function and for the analysis of evolutionary relationships. Motif-based search methods play a crucial role in establishing the connections between proteins that are particularly useful for distant relationships. This paper reports SCANMOT, a web-based server that searches for similarities between proteins by simultaneous matching of multiple motifs. SCANMOT searches for similar sequences in entire sequence databases using multiple conserved regions and utilizes inter-motif spacing as restraints. The SCANMOT server is available via http://www.ncbs.res.in/~faculty/mini/scanmot/scanmot.html.
摘要
确定蛋白质之间的相似性对于研究序列、结构和功能之间的关系以及分析进化关系非常重要。基于基序的搜索方法在建立蛋白质之间的联系方面起着关键作用，这对于远缘关系尤为有用。本文报道了SCANMOT，一个基于网络的服务器，它通过同时匹配多个基序来搜索蛋白质之间的相似性。SCANMOT使用多个保守区域在整个序列数据库中搜索相似序列，并利用基序间的间距作为限制条件。可通过http://www.ncbs.res.in/~faculty/mini/scanmot/scanmot.html访问SCANMOT服务器。
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