Shah P M, Sen S, Perlmuter L C, Feller A
Gastroenterology Section, Medical Service, VA Medical Center, 3001 Green Bay Road, North Chicago, IL 60064, USA.
J Nutr Health Aging. 2005 Jul-Aug;9(4):255-9.
Percutaneous Endoscopic Gastrostomy (PEG) is a widely used technique for enteral feeding in nursing home patients. Several factors including malnutrition, hypoalbuminemia, older age, number of co-morbidities and cognitive impairment adversely affect survival.
This study evaluated the relative impact of age, serum albumin, number of co-morbid illnesses and dementia on survival in male nursing home patients who had undergone percutaneous endoscopic gastrostomy (PEG).
In a retrospective study the hospital records of all North Chicago Veterans Affair (VA) male nursing home residents (n=88) who had PEG placed between 1990 through 2000 were reviewed. Of the 88 charts reviewed, 17 were eliminated from analysis due to incomplete data. Following data was examined: Age, serum albumin, number of co-morbid illnesses, presence of dementia, survival in years following PEG placement.
Advancing age was associated with increasing probability of dementia and increased number of co-morbidities. Post PEG survival decreased with increasing age, with lower serum albumin, and increased number of co-morbidities. Age and serum albumin were strong predictors of survival in PEG recipients without the diagnosis of dementia. However, in PEG recipients with a diagnosis of dementia, age and serum albumin no longer predicted survival. Dementia appears to attenuate the effects of age and serum albumin on survival following PEG placement.
In the presence of dementia, none of the usual predictors of survival in PEG recipients remain significant.
经皮内镜下胃造口术(PEG)是养老院患者肠内营养的一种广泛应用的技术。包括营养不良、低白蛋白血症、高龄、合并症数量和认知障碍在内的几个因素对生存率有不利影响。
本研究评估年龄、血清白蛋白、合并疾病数量和痴呆对接受经皮内镜下胃造口术(PEG)的男性养老院患者生存率的相对影响。
在一项回顾性研究中,对1990年至2000年间在北芝加哥退伍军人事务部(VA)养老院接受PEG治疗的所有男性居民(n = 88)的医院记录进行了审查。在审查的88份病历中,由于数据不完整,17份被排除在分析之外。检查了以下数据:年龄、血清白蛋白、合并疾病数量、痴呆的存在、PEG放置后数年的生存率。
年龄增长与痴呆发生率增加和合并症数量增加相关。PEG放置后的生存率随着年龄增加、血清白蛋白降低和合并症数量增加而降低。在未诊断为痴呆的PEG接受者中,年龄和血清白蛋白是生存率的强预测因素。然而,在诊断为痴呆的PEG接受者中,年龄和血清白蛋白不再能预测生存率。痴呆似乎减弱了年龄和血清白蛋白对PEG放置后生存率的影响。
在存在痴呆的情况下,PEG接受者中通常的生存率预测因素均不再具有显著性。