双侧非典型导管增生，男性乳房肥大症中的偶然发现——病例报告及文献综述

Bilateral atypical ductal hyperplasia, an incidental finding in gynaecomastia--case report and literature review.

作者信息

Prasad Vani, M King John, McLeay William, Raymond Wendy, Cooter Rodney D

机构信息

Waverley House Plastic Surgery Centre, 360, South Terrace, Adelaide SA 5000, Australia.

出版信息

Breast. 2005 Aug;14(4):317-21. doi: 10.1016/j.breast.2005.04.010.

DOI:10.1016/j.breast.2005.04.010

PMID:15985368

Abstract

Male breast cancer is a rare disease. Atypical ductal hyperplasia (ADH) in men is much rarer, and bilateral involvement is exceptional. A 20-year-old male presented with bilateral gynaecomastia who underwent subcutaneous mastectomies and histopathology revealed bilateral ADH. At 24 months, completion mastectomies were performed on both sides. The residual breast tissue revealed ADH similar to the initial specimen. ADH in women increases the risk of breast cancer by four to five times. To our knowledge, this is the first case report of bilateral ADH in a gynaecomastia specimen.

摘要

男性乳腺癌是一种罕见疾病。男性的非典型导管增生（ADH）更为罕见，双侧受累的情况更是罕见。一名20岁男性因双侧乳腺增生前来就诊，接受了皮下乳房切除术，组织病理学检查显示双侧ADH。24个月时，双侧进行了根治性乳房切除术。残留的乳腺组织显示出与初始标本相似的ADH。女性的ADH会使患乳腺癌的风险增加4至5倍。据我们所知，这是第一例在乳腺增生标本中出现双侧ADH的病例报告。