Koyu Ahmet, Ozguner Fehmi, Cesur Gokhan, Gokalp Osman, Mollaoglu Hakan, Caliskan Sadettin, Delibas Namik
Department of Physiology, Suleyman Demirel University, School of Medicine, Isparta, Turkey.
Toxicol Ind Health. 2005 Mar;21(1-2):27-31. doi: 10.1191/0748233705th212oa.
In this study, the effects of exposure to a 900 MHz and 1800 MHz electromagnetic field (EMF) on serum nocturnal melatonin levels of adult male Sprague-Dawley rats were studied. Thirty rats were used in three independent groups, 10 of which were exposed to 900 MHz, 10 of which were exposed to 1800 MHz and 10 of which were sham-exposed (control). The exposures were performed 30 min/day, for five days/week for four weeks to 900 MHz or 1800 MHz EMF Control animals were kept under the same environmental conditions as the study groups except with no EMF exposure. The concentration of nocturnal melatonin in the rat serum was measured by using a radioimmunoassay method. There were no statistically significant differences in serum melatonin concentrations between the 900 MHz EMF group and the sham-exposed group (P > 0.05). The values at 12:00 pm were 39.11 +/- 6.5 pg/mL in the sham-exposed group and 34.97 +/- 5.1 pg/mL in the 900 MHz EMF-exposed group. Also, there were no statistically significant differences in serum melatonin concentrations between the sham-exposed group and the 1800 MHz EMF-exposed group (P > 0.05). The values at 12:00 pm were 39.11 +/- 6.5 pg/mL in the sham-exposed group and 37.96 +/- 7.4 pg/mL in the exposed group. These results indicate that mobile phones, emitting 900 and 1800 MHz EMF, have no effect on nocturnal serum melatonin levels in rats.
在本研究中,研究了暴露于900兆赫和1800兆赫电磁场(EMF)对成年雄性Sprague-Dawley大鼠血清夜间褪黑素水平的影响。30只大鼠被分为三个独立组,其中10只暴露于900兆赫,10只暴露于1800兆赫,10只为假暴露(对照组)。暴露每天进行30分钟,每周5天,持续4周,暴露于900兆赫或1800兆赫的电磁场。对照动物饲养在与研究组相同的环境条件下,但不暴露于电磁场。采用放射免疫分析法测定大鼠血清中夜间褪黑素的浓度。900兆赫电磁场组与假暴露组之间血清褪黑素浓度无统计学显著差异(P>0.05)。下午12:00时,假暴露组的值为39.11±6.5皮克/毫升,900兆赫电磁场暴露组为34.97±5.1皮克/毫升。此外,假暴露组与1800兆赫电磁场暴露组之间血清褪黑素浓度也无统计学显著差异(P>0.05)。下午12:00时,假暴露组的值为39.11±6.5皮克/毫升,暴露组为37.96±7.4皮克/毫升。这些结果表明,发射900兆赫和1800兆赫电磁场的手机对大鼠夜间血清褪黑素水平没有影响。