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攻击性行为:从实验室到临床。何去何从?

Aggressive behavior: from laboratory to clinic. Quo vadit?

作者信息

Eichelman B

机构信息

Department of Psychiatry, Temple University School of Medicine, Philadelphia, Pa 19140.

出版信息

Arch Gen Psychiatry. 1992 Jun;49(6):488-92. doi: 10.1001/archpsyc.1992.01820060068012.

DOI:10.1001/archpsyc.1992.01820060068012
PMID:1599375
Abstract

This article sets forth two theses: (1) that animal models of aggressive behavior have utility in fostering and guiding human aggression research; and (2) that clinical violence research should now focus on the severely and repetitively aggressive patients for study and therapeutic research. Animal models are reviewed in terms of typology; studies of temperament; the role of sensory cues; neuroanatomy, neurochemistry, and neuroendocrinology; studies of stress; and studies of social conditions. Examples are presented that have implications and potential utility for human research. Clinical approaches to the study of human aggressive behavior are examined and five suggestions are made to enhance the efficacy and utility of clinically relevant aggression research.

摘要

本文提出两个论点

(1)攻击性行为的动物模型在促进和指导人类攻击行为研究方面具有实用性;(2)临床暴力研究现在应聚焦于严重且反复攻击的患者,以进行研究和治疗性探索。文章从类型学、气质研究、感官线索的作用、神经解剖学、神经化学和神经内分泌学、应激研究以及社会环境研究等方面对动物模型进行了综述。文中列举了一些对人类研究具有启示意义和潜在实用性的例子。对人类攻击行为研究的临床方法进行了审视,并提出了五条建议,以提高临床相关攻击行为研究的有效性和实用性。

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