van der Meijden Adrian P M, Sylvester Richard, Oosterlinck Willem, Solsona Eduardo, Boehle Andreas, Lobel Bernard, Rintala Erkki
Department of Urology, Jeroen Bosch Hospital, Hertogenbosch, The Netherlands.
Eur Urol. 2005 Sep;48(3):363-71. doi: 10.1016/j.eururo.2005.05.011.
On behalf of the European Association of Urology (EAU), guidelines for the diagnosis, therapy and follow-up of patients with urothelial carcinoma in situ (CIS) have been established.
The recommendations in these guidelines are based on a recent comprehensive overview and meta-analysis in which two panel members have been involved (RS and AVDM). A systematic literature search was conducted using Medline, the US Physicians' Data Query (PDQ), the Cochrane Central Register of Controlled Trials, and reference lists in trial publications and review articles.
Recommendations are provided for the diagnosis, conservative and radical surgical treatment, and follow-up of patients with CIS. Levels of evidence are influenced by the lack of large randomized trials in the treatment of CIS.
代表欧洲泌尿外科学会（EAU），制定了尿路上皮原位癌（CIS）患者的诊断、治疗及随访指南。
这些指南中的建议基于近期的一项全面综述和荟萃分析，两名小组成员（RS和AVDM）参与其中。使用Medline、美国医师数据查询（PDQ）、Cochrane对照试验中心注册库以及试验出版物和综述文章中的参考文献列表进行了系统的文献检索。
提供了关于CIS患者诊断、保守及根治性手术治疗和随访的建议。证据水平受到CIS治疗中缺乏大型随机试验的影响。
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