耻垢分枝杆菌的F1Fo-ATP合酶对生长至关重要。
The F1Fo-ATP synthase of Mycobacterium smegmatis is essential for growth.
作者信息
Tran Sieu L, Cook Gregory M
机构信息
Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand.
出版信息
J Bacteriol. 2005 Jul;187(14):5023-8. doi: 10.1128/JB.187.14.5023-5028.2005.
Abstract
The F(1)F(o)-ATP synthase plays an important role in a number of vital cellular processes in plants, animals, and microorganisms. In this study, we constructed a DeltaatpD mutant of Mycobacterium smegmatis and demonstrated that atpD encoding the beta subunit of the F(1)F(o)-ATP synthase is an essential gene in M. smegmatis during growth on nonfermentable and fermentable carbon sources.
摘要
F(1)F(o)-ATP合酶在植物、动物和微生物的许多重要细胞过程中发挥着重要作用。在本研究中，我们构建了耻垢分枝杆菌的DeltaatpD突变体，并证明编码F(1)F(o)-ATP合酶β亚基的atpD是耻垢分枝杆菌在非发酵和发酵碳源上生长期间的必需基因。
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