Harada N, Dohmen K, Itoh H, Ohshima T, Yamamoto H, Nagano M, Iwata Y, Hachisuka K, Ishibashi H
Department of Internal Medicine, Kyushu Koseinenkin Hospital, Kitakyushu, Japan.
Intern Med. 1992 Feb;31(2):289-93. doi: 10.2169/internalmedicine.31.289.
Primary biliary cirrhosis (PBC) was diagnosed in two siblings, a 42-year-old male and his 49-year-old sister. Furthermore, they were complicated with three types of autoimmune diseases: polymyositis, Hashimoto's thyroiditis and vasculitis of the right axillary artery. Although PBC is often associated with other autoimmune diseases, reports of the association with polymyositis and vasculitis syndrome are rare. Familial clustering of PBC with autoimmune diseases is also rare.
两名患有原发性胆汁性肝硬化（PBC）的患者为姐弟，分别是42岁的男性和49岁的女性。此外，他们还并发了三种自身免疫性疾病：多发性肌炎、桥本甲状腺炎和右腋动脉血管炎。虽然PBC常与其他自身免疫性疾病相关，但关于其与多发性肌炎和血管炎综合征关联的报道却很少。PBC与自身免疫性疾病的家族聚集现象也很罕见。
