Nohira Tomoyoshi, Kim Seiichi, Nakai Hiromi, Okabe Kazuhiro, Nohira Tomoo, Yoneyama Kuniyoshi
Department of Obstetrics and Gynecology, Hachioji Medical Center of Tokyo Medical University, Tate-machi 1163, Hachioji-si, Tokyo 193-0998, Japan.
Diabetes Res Clin Pract. 2006 Jan;71(1):75-81. doi: 10.1016/j.diabres.2005.05.011. Epub 2005 Jul 6.
The recurrence rate of GDM among women in Japan who had GDM or one abnormal value on 75 g oral glucose tolerance test (OAV) during an initial pregnancy is unclear. We therefore sought to determine the recurrence rate and risk factors of recurrent GDM by evaluating 32 patients with GDM and 37 with OAV in their index pregnancies. Medical records and chemical data were compared between patients with and without GDM in their subsequent pregnancies. The recurrence rate from index GDM and OAV were 65.6% and 40.5%. Age, BMI before pregnancy, an increased weight gain between pregnancies and a short interval between pregnancies were risk factors for recurrence from the initial GDM. An increased weight gain between pregnancies and a short interval between pregnancies were risk factors of development to GDM from the initial OAV. We concluded that the control of weight gain and interval between pregnancies could be important to reduce GDM recurrence.
日本初孕时患有妊娠期糖尿病（GDM）或口服75克葡萄糖耐量试验（OAV）有一项异常值的女性中GDM的复发率尚不清楚。因此，我们通过评估32例妊娠期糖尿病患者和37例口服葡萄糖耐量试验异常患者的首次妊娠情况，试图确定复发性GDM的复发率和危险因素。比较了后续妊娠中有或无GDM患者的病历和化学数据。首次GDM和OAV的复发率分别为65.6%和40.5%。年龄、孕前体重指数、孕期体重增加过多以及妊娠间隔时间短是首次GDM复发的危险因素。孕期体重增加过多以及妊娠间隔时间短是首次OAV发展为GDM的危险因素。我们得出结论，控制孕期体重增加和妊娠间隔时间对于降低GDM复发可能很重要。
