Odeleye O E, Odeleye A A
Department of Family and Community Medicine, University of Arizona Health Sciences Center, Tucson 85724.
Eur J Clin Nutr. 1992 May;46(5):367-71.
The effect of caloreen (glucose polymer) supplementation on indicators of iron status during protein-energy malnutrition was studied. Sixty-four children with moderate protein energy malnutrition (PEM) were fed diets supplemented with caloreen or starch (control) for 14 days, following which iron status as packed cell volume (PCV), haemoglobin (Hb), serum iron, total iron binding capacity (TIBC), serum ferritin, and urinary iron levels were determined. Caloreen supplementation significantly increased (P less than 0.05). PCV, serum iron and serum ferritin and decreased (P less than 0.05) TIBC. Also, there was a tendency for Hb to increase and urinary iron to decrease in this group, but these changes were not statistically significant. Such changes were not observed in the starch-placebo-supplemented group. It is concluded that caloreen supplementation to PEM children increases body iron status. These increases in the indices of iron status may contribute to an early recovery of anaemia associated with PEM. Prolonged supplementation of a regular diet with glucose early in the development of PEM may retard the development and severity of anaemia in children.
研究了补充卡洛林（葡萄糖聚合物）对蛋白质 - 能量营养不良期间铁状态指标的影响。64名中度蛋白质能量营养不良（PEM）儿童被给予补充了卡洛林或淀粉（对照）的饮食14天，之后测定铁状态指标，如红细胞压积（PCV）、血红蛋白（Hb）、血清铁、总铁结合力（TIBC）、血清铁蛋白和尿铁水平。补充卡洛林显著增加了（P小于0.05）PCV、血清铁和血清铁蛋白，并降低了（P小于0.05）TIBC。此外，该组中Hb有增加趋势，尿铁有减少趋势，但这些变化无统计学意义。在补充淀粉安慰剂的组中未观察到此类变化。得出的结论是，给PEM儿童补充卡洛林可提高机体铁状态。铁状态指标的这些增加可能有助于与PEM相关的贫血的早期恢复。在PEM发展早期，长期在常规饮食中补充葡萄糖可能会延缓儿童贫血的发展和严重程度。
