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[足月孕妇及其新生儿的铁营养状况]

[Status of iron nutrition in term pregnant women and their newborns].

作者信息

Wu Y

出版信息

Zhonghua Fu Chan Ke Za Zhi. 1989 Mar;24(2):81-4, 123-4.

PMID:2758910
Abstract

Haemoglobin (Hb), free erythrocyte protoporphyrin (FEP), ratio of FEP and Hb (FEP/Hb), serum ferritin (SF) packed red cell volume (PCV), serum iron (SI), total iron binding capacity (TIBC), transferrin saturation (TS) were evaluated in 170 healthy pregnant women and their full-term babies. The pregnant women were devided into normal and iron deficient groups. The status of iron nutrition of babies of normal mothers and mothers with iron deficiency anemia (IDA) was compared. It showed that the decreased value of PCV in late pregnancy was mainly related to IDA. While the values of SF, FEP/Hb and Hb were more sensitive for detecting pregnancy associated IDA, the values of FEP, FEP/Hb and Hb in babies of IDA mothers were significantly higher than those in babies of normal mothers. Maternal iron status bore no significant correlation with the iron store of their babies. However, Hb less than 11 g/L, FEP/Hb greater than 4.5 micrograms/g, FEP greater than 0.92 mumol/L or SF less than 50 micrograms/L in early pregnancy were indications for iron supplementation.

摘要

对170名健康孕妇及其足月婴儿进行了血红蛋白(Hb)、游离红细胞原卟啉(FEP)、FEP与Hb的比值(FEP/Hb)、血清铁蛋白(SF)、红细胞压积(PCV)、血清铁(SI)、总铁结合力(TIBC)、转铁蛋白饱和度(TS)的评估。将孕妇分为正常组和缺铁组。比较了正常母亲和缺铁性贫血(IDA)母亲所生婴儿的铁营养状况。结果显示,妊娠晚期PCV的降低主要与IDA有关。虽然SF、FEP/Hb和Hb的值对检测妊娠相关IDA更敏感,但IDA母亲所生婴儿的FEP、FEP/Hb和Hb值明显高于正常母亲所生婴儿。母亲的铁状态与其婴儿的铁储备无显著相关性。然而,妊娠早期Hb低于11g/L、FEP/Hb大于4.5μg/g、FEP大于0.92μmol/L或SF低于50μg/L是补铁的指征。

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