O'Connor Kate, Hamm Jeff P, Kirk Ian J
Research Centre for Cognitive Neuroscience, Department of Psychology, University of Auckland, Auckland, New Zealand.
Brain Cogn. 2005 Oct;59(1):82-95. doi: 10.1016/j.bandc.2005.05.004. Epub 2005 Jul 11.
Past research has found evidence for face and emotional expression processing differences between individuals with Asperger's syndrome (AS) and neurotypical (NT) controls at both the neurological and behavioural levels. The aim of the present study was to examine the neurophysiological basis of emotional expression processing in children and adults with AS relative to age- and gender-matched NT controls. High-density event-related potentials were recorded during explicit processing of happy, sad, angry, scared, and neutral faces. Adults with AS were found to exhibit delayed P1 and N170 latencies and smaller N170 amplitudes in comparison to control subjects for all expressions. This may reflect impaired holistic and configural processing of faces in AS adults. However, these differences were not observed between AS and control children. This may result from incomplete development of the neuronal generators of these ERP components and/or early intervention.
过去的研究已发现证据表明，阿斯伯格综合征（AS）患者与神经典型（NT）对照者在神经学和行为层面上，在面部及情绪表达处理方面存在差异。本研究的目的是，相对于年龄和性别匹配的NT对照者，研究患有AS的儿童和成人在情绪表达处理方面的神经生理学基础。在对开心、悲伤、愤怒、恐惧和中性面部表情进行明确处理的过程中，记录了高密度事件相关电位。结果发现，与对照受试者相比，患有AS的成年人在处理所有表情时，P1和N170潜伏期延迟，N170波幅较小。这可能反映出AS成年人对面部的整体和构型处理受损。然而，在AS儿童和对照儿童之间未观察到这些差异。这可能是由于这些ERP成分的神经发生器发育不完全和/或早期干预所致。
