Chiesa R, Marone E M, Limoni C, Volonté M, Schaefer E, Petrini O
Scientific Institute H. San Raffaele, Vita-Salute University, Milan, Italy.
Eur J Vasc Endovasc Surg. 2005 Oct;30(4):422-9. doi: 10.1016/j.ejvs.2005.06.005.
To assess the relationship between sex, age, geographical region, lower limb symptoms and the presence of trunk varicose veins and venous incompetence.
Cross-sectional population study in 24 cities in the North, centre and South of Italy.
Five thousand two hundred and forty-seven people were selected during spring and summer 2003 by advertising on television, in newspapers, and by leaflets in 24 Italian cities. In all 5187 (4457 [85.9%] women and 730 men [14.1%]) volunteers were assessed. The median age was 54 (range: 18-90) years for the women and 61 (range: 18-89) years for the men.
Self-administered questionnaire on subjective symptoms of chronic venous insufficiency (CVI) in the lower limbs, and clinical examination, including colour duplex ultrasonography to assess the presence and severity of varicose veins.
Overall only 22.7% of the subjects examined were free of visible signs of venous disease, with approximately 53% of the population over 50 years of age showing some venous reflux. People living in Southern Italy were more severely affected than those living in the North. Varicosities and telangiectases were the most frequent objective signs in both sexes. Trunk varicosities (27%) and saphenous reflux (41%) increased with age and were more common in men; in contrast, minor objective symptoms such as telangiectases (70%), as well as subjective symptoms such as heavy (79%) and tired legs (78%), were more common in women and were not age-related.
Venous disease is very common in Italy, in particular in people living in the South. A correlation between varicose veins and venous incompetence is more marked in men, while minor objective and subjective symptoms prevail in women. The findings from this non-random sample closely match results from previous studies, in which random sampling was used.
评估性别、年龄、地理区域、下肢症状与躯干静脉曲张及静脉功能不全之间的关系。
在意大利北部、中部和南部的24个城市进行的横断面人群研究。
2003年春夏期间，通过电视、报纸广告以及在意大利24个城市发放传单的方式，选取了5247人。共评估了5187名志愿者（4457名女性[85.9%]和730名男性[14.1%]）。女性的年龄中位数为54岁（范围：18 - 90岁），男性为61岁（范围：18 - 89岁）。
采用关于下肢慢性静脉功能不全（CVI）主观症状的自填问卷，并进行临床检查，包括彩色双功超声检查以评估静脉曲张的存在和严重程度。
总体而言，仅22.7%的受检者没有明显的静脉疾病体征，约53%的50岁以上人群存在一些静脉反流。生活在意大利南部的人比北部的人受影响更严重。静脉曲张和毛细血管扩张是两性中最常见的客观体征。躯干静脉曲张（27%）和大隐静脉反流（41%）随年龄增加，且在男性中更常见；相比之下，毛细血管扩张（70%）等轻微客观症状以及腿部沉重感（79%）和疲劳感（78%）等主观症状在女性中更常见，且与年龄无关。
静脉疾病在意大利非常普遍，尤其是在生活在南部的人群中。静脉曲张与静脉功能不全之间的相关性在男性中更为明显，而轻微的客观和主观症状在女性中更为普遍。这个非随机样本的研究结果与之前采用随机抽样的研究结果非常吻合。
