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计算中子俘获治疗建模中COG和MCNP代码的比较,第一部分:硼中子俘获治疗模型

A comparison of the COG and MCNP codes in computational neutron capture therapy modeling, Part I: boron neutron capture therapy models.

作者信息

Culbertson C N, Wangerin K, Ghandourah E, Jevremovic T

机构信息

School of Physics and Astronomy, University of Birmingham, Birmingham, UK.

出版信息

Health Phys. 2005 Aug;89(2):127-34. doi: 10.1097/01.hp.0000160544.76255.78.

DOI:10.1097/01.hp.0000160544.76255.78
PMID:16010123
Abstract

The goal of this study was to evaluate the COG Monte Carlo radiation transport code, developed and tested by Lawrence Livermore National Laboratory, for neutron capture therapy related modeling. A boron neutron capture therapy model was analyzed comparing COG calculational results to results from the widely used MCNP4B (Monte Carlo N-Particle) transport code. The approach for computing neutron fluence rate and each dose component relevant in boron neutron capture therapy is described, and calculated values are shown in detail. The differences between the COG and MCNP predictions are qualified and quantified. The differences are generally small and suggest that the COG code can be applied for BNCT research related problems.

摘要

本研究的目的是评估由劳伦斯利弗莫尔国家实验室开发并测试的COG蒙特卡罗辐射输运代码,用于与中子俘获治疗相关的建模。分析了一个硼中子俘获治疗模型,将COG计算结果与广泛使用的MCNP4B(蒙特卡罗N粒子)输运代码的结果进行比较。描述了计算硼中子俘获治疗中相关的中子注量率和各剂量分量的方法,并详细给出了计算值。对COG和MCNP预测之间的差异进行了定性和定量分析。差异通常较小,这表明COG代码可应用于与硼中子俘获治疗研究相关的问题。

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