CT图像在BNCT计算中的应用：BNCT治疗计划系统的开发及其在体素模型剂量计算中的应用

Use of the CT images for BNCT calculation: development of BNCT treatment planning system and its applications to dose calculation for voxel phantoms.

作者信息

Park Sung Ho, Han Chi Young, Kim Soon Young, Kim Jong Kyung

机构信息

Department of Nuclear Engineering, Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul, 133-791, Korea.

出版信息

Radiat Prot Dosimetry. 2004;110(1-4):661-7. doi: 10.1093/rpd/nch235.

DOI:10.1093/rpd/nch235

PMID:15353727

Abstract

A BNCT (Boron Neutron Capture Therapy) treatment planning system (BTPS) was developed for BNCT study and treatment planning. Three kinds of CT images, VHP, PINNACLE and DICOM images, were employed to make voxel phantoms for BNCT patient treatment using the BTPS. The thermal neutron, fast neutron, gamma and boron doses are calculated and background, tissue, and tumour doses for idealised standard reactor neutron field (ISRNF) neutron beam were calculated by using BTPS and MCNP code. It was noted that the total computing times needed for BNCT analysis could be greatly reduced since the BTPS system provides a dose analysis tool and a lengthy MCNP input in a short time. It is, thus, expected that the BTPS can significantly contribute the BNCT study for the treatment of patients.

摘要

为硼中子俘获疗法（BNCT）研究及治疗规划开发了一种BNCT治疗计划系统（BTPS）。利用三种CT图像，即VHP、PINNACLE和DICOM图像，通过BTPS制作用于BNCT患者治疗的体素模型。计算了热中子、快中子、伽马和硼剂量，并使用BTPS和MCNP代码计算了理想化标准反应堆中子场（ISRNF）中子束的本底、组织和肿瘤剂量。值得注意的是，由于BTPS系统能在短时间内提供剂量分析工具和冗长的MCNP输入，因此BNCT分析所需的总计算时间可大幅减少。因此，预计BTPS能为BNCT患者治疗研究做出重大贡献。