Meyer-Bahlburg Heino F L
New York State Psychiatric Institute, New York, NY 10032, USA.
Arch Sex Behav. 2005 Aug;34(4):423-38. doi: 10.1007/s10508-005-4342-9.
This review addresses the long-term gender outcome of gender assignment of persons with intersexuality and related conditions. The gender assignment to female of 46,XY newborns with severe genital abnormalities despite a presumably normal-male prenatal sex-hormone milieu is highly controversial because of variations in assumptions about the role of biological factors in gender identity formation. This article presents a literature review of gender outcome in three pertinent conditions (penile agenesis, cloacal exstrophy of the bladder, and penile ablation) in infancy or early childhood. The findings clearly indicate an increased risk of later patient-initiated gender re-assignment to male after female assignment in infancy or early childhood, but are nevertheless incompatible with the notion of a full determination of core gender identity by prenatal androgens.
本综述探讨了两性畸形及相关疾病患者性别指定的长期性别结局。尽管产前性激素环境可能正常，但对于46,XY新生儿存在严重生殖器异常却指定为女性的情况极具争议，原因在于关于生物学因素在性别认同形成中作用的假设存在差异。本文对婴儿期或幼儿期三种相关病症（阴茎发育不全、膀胱泄殖腔外翻和阴茎切除）的性别结局进行了文献综述。研究结果明确表明，婴儿期或幼儿期指定为女性的患者，日后主动要求重新指定为男性的风险增加，但这仍与产前雄激素完全决定核心性别认同的观点不符。
