Costantini A
Unit of Physiopathology and Therapy of Pain, SS. Annunziata Hospital, and Department of Anesthesia and Resuscitation, G. D'Annunzio University, Chieti, Italy.
Minerva Anestesiol. 2005 Jul-Aug;71(7-8):471-4.
Spinal cord stimulation (SCS) is a neuromodulation technique using electricity, proposed for the first time by Shealy in 1967, as an alternative to neuroablation. Technological improvements in the last 20 years (percutaneous electrodes, single and dual leads, octopolar electrodes, high energy internal pulse generators) have allowed to obtain good results with SCS in various clinical situations of chronic pain. The main clinical indications to SCS are: vascular pain--refractory angina and peripheral vascular diseases (PVD); rachidian pain--failed back surgery syndrome (FBSS), degenerative low back leg pain (LBLP), nerve root lesions, incomplete spine lesions, spinal stenosis; neuropathic pain; chronic regional pain syndrome (CRPS) type 1 and type 2; perineal pain and urological diseases (urge-incontinence, interstitial cystitis). There are important differences between Europe and USA in the SCS use in various indications, especially about PVD. Really, in Europe this technique has been widely used and, finally, there are prospective studies establishing the utility of SCS in: limb survival; pain control; regression to Fontaine stage II; improvement of free interval of claudication. All of this is going to change the attitude towards SCS in USA, where the amputation incidence for critical ischaemia is considerably higher than in Europe. An indication to SCS not very mentioned in literature and that seems to have good results is LBLP due to acquired or mixed (constitutional-acquired) spinal stenosis. In this situation SCS seems to improve notably pain control and quality of life index of patients.
脊髓刺激(SCS)是一种利用电的神经调节技术,由谢利在1967年首次提出,作为神经消融的替代方法。过去20年的技术进步(经皮电极、单极和双极导联、八极电极、高能内置脉冲发生器)使得SCS在各种慢性疼痛临床情况下都能取得良好效果。SCS的主要临床适应症包括:血管性疼痛——顽固性心绞痛和外周血管疾病(PVD);脊柱疼痛——腰椎手术失败综合征(FBSS)、退行性腰腿痛(LBLP)、神经根病变、不完全性脊柱病变、椎管狭窄;神经性疼痛;1型和2型慢性区域疼痛综合征(CRPS);会阴疼痛和泌尿系统疾病(急迫性尿失禁、间质性膀胱炎)。欧洲和美国在SCS用于各种适应症方面存在重要差异,尤其是在PVD方面。实际上,在欧洲这项技术已被广泛应用,最终有前瞻性研究证实SCS在以下方面的效用:肢体存活;疼痛控制;回归至Fontaine II期;改善间歇性跛行的自由间隔时间。所有这些都将改变美国对SCS的态度,在美国,严重缺血的截肢发生率明显高于欧洲。文献中较少提及但似乎效果良好的SCS适应症是由获得性或混合性(先天性-获得性)椎管狭窄引起的LBLP。在这种情况下,SCS似乎能显著改善患者的疼痛控制和生活质量指数。