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心血管疾病中的脊髓刺激

Spinal cord stimulation in cardiovascular disease.

作者信息

Augustinsson L E, Linderoth B, Mannheimer C, Eliasson T

机构信息

Ostra Hospital, Goteborg, Sweden.

出版信息

Neurosurg Clin N Am. 1995 Jan;6(1):157-65.

PMID:7696871
Abstract

Spinal cord stimulation in ischemic pain conditions has proved to be an effective method of treatment for many patients. The indications are ischemic pain in the extremities from peripheral vascular disease and angina pectoris. The long-term results show that the response rate for ischemic pain is 70% to 90%, while the corresponding results for neuropathic pain average approximately 50% to 70%, which actually makes ischemic pain a very good indication for SCS. SCS system implantation is a safe and quick operation performed under local anesthesia and well tolerated by the patient. A total implant of the lead and the pulse-generator in one stage seldom takes more than 1 hour. High sterility and prophylactic antibiotics are prerequisites to avoid postoperative problems. In atherosclerosis, SCS should be regarded as a method supplementary to vascular surgery, to be used for symptom recurrence after treatment or when there are technical obstacles to reconstructive surgery. SCS has proven to be extremely effective for the relief of ischemic rest pain, which constitutes the most severe problem for these patients. Today it is estimated that more than 7000 implants for PVD have been done in Europe. In a prospective randomized study, Jivegård et al have shown that SCS is a limb-saving treatment. For angina pectoris, SCS by now has become a routine supplementary method to conventional medical and surgical treatment. The technique is clinically effective, and several studies have shown decreased myocardial ischemia and decreased anginal pain during treatment. It is probable that the use of SCS in refractory angina will increase considerably in the 1990s.

摘要

脊髓刺激疗法在治疗缺血性疼痛方面已被证明对许多患者是一种有效的治疗方法。其适应症为外周血管疾病引起的肢体缺血性疼痛和心绞痛。长期结果表明,缺血性疼痛的缓解率为70%至90%,而神经性疼痛的相应缓解率平均约为50%至70%,这实际上使缺血性疼痛成为脊髓刺激疗法的一个很好的适应症。脊髓刺激系统植入是一种在局部麻醉下进行的安全、快速的手术,患者耐受性良好。一次性完成电极和脉冲发生器的完全植入很少需要超过1小时。高度无菌和预防性使用抗生素是避免术后问题的先决条件。在动脉粥样硬化中,脊髓刺激疗法应被视为血管手术的一种辅助方法,用于治疗后症状复发或重建手术存在技术障碍时。脊髓刺激疗法已被证明对缓解缺血性静息痛极为有效,而缺血性静息痛是这些患者最严重的问题。如今估计在欧洲已进行了7000多例用于外周血管疾病的植入手术。在一项前瞻性随机研究中,耶维加德等人表明脊髓刺激疗法是一种保肢治疗方法。对于心绞痛,脊髓刺激疗法现已成为传统药物和手术治疗的常规辅助方法。该技术在临床上是有效的,几项研究表明在治疗期间心肌缺血减少,心绞痛减轻。在20世纪90年代,脊髓刺激疗法在难治性心绞痛中的应用可能会大幅增加。

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