Saligaut C, Salbert G, Bailhache T, Bennani S, Jego P
Laboratoire de Physiologie des Régulations, U.R.A. CNRS 256, Université de Rennes I, France.
Gen Comp Endocrinol. 1992 Feb;85(2):261-8. doi: 10.1016/0016-6480(92)90010-h.
Brain serotonin (5HT) and dopamine (DA) turnover were studied at various stages of the reproductive cycle of the female rainbow trout by simultaneous determination by HPLC of neurotransmitters and major related metabolites. An increase of 5HT turnover in telencephalon and hypothalamus and a decrease of DA turnover in pituitary and hypothalamus were observed during the periovulatory period. Some changes also occurred during vitellogenesis: decreased 5HT metabolite in telencephalon and preoptic area and increased DA content in preoptic area. These data suggest that physiological fluctuations of biogenic amines could be involved in both ovarian recrudescence and ovulation, with major effects on the hypothalamo-hypophysial complex during the periovulatory period.
通过高效液相色谱法同时测定神经递质及其主要相关代谢物，研究了雌性虹鳟鱼在生殖周期各阶段的脑血清素（5HT）和多巴胺（DA）周转率。在排卵期前后，观察到端脑和下丘脑的5HT周转率增加，垂体和下丘脑的DA周转率降低。在卵黄发生期也出现了一些变化：端脑和视前区的5HT代谢物减少，视前区的DA含量增加。这些数据表明，生物胺的生理波动可能参与卵巢复壮和排卵过程，在排卵期对下丘脑 - 垂体复合体有主要影响。
