恶性淋巴瘤导致的外阴破坏

Vulvar destruction by malignant lymphoma.

作者信息

Tuder R M

机构信息

Anatomic Pathologic Division, INCOR, Hospital das Clínicas, University of São Paulo School of Medicine, Brazil.

出版信息

Gynecol Oncol. 1992 Apr;45(1):52-7. doi: 10.1016/0090-8258(92)90490-a.

DOI:10.1016/0090-8258(92)90490-a

PMID:1601334

Abstract

Two cases of vulvar and perineal destruction by malignant lymphoma are described. The first case was of an untreated 4-year-long vulvar destruction due to a kappa-positive lymphoplasmacytic lymphoma that ultimately resulted in the death of the patient. The second patient had involvement of the vulva and perineum by an angiocentric small and large mixed-cell lymphoma. Aggressive chemotherapy induced regression and healing of the lesions in the second case. Delayed diagnosis and inappropriate management of lymphomas in the vulva may lead to widely destructive disease of the lower female genital tract.

摘要

本文描述了两例外阴和会阴恶性淋巴瘤破坏的病例。第一例是一名未经治疗的4年病程的外阴破坏，病因是κ阳性淋巴浆细胞淋巴瘤，最终导致患者死亡。第二例患者患有血管中心性大小混合细胞淋巴瘤累及外阴和会阴。积极化疗使第二例患者的病变消退并愈合。外阴淋巴瘤的延迟诊断和不恰当处理可能导致女性下生殖道广泛破坏性疾病。