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外阴淋巴瘤:麻省理工学院罕见癌症研究小组综述

Lymphomas of the Vulva: A Review of the MITO Rare Cancer Group.

作者信息

Magazzino Francescapaola, Aristei Cynthia, Passarelli Anna, Pierini Antonio, De Giorgi Ugo, Martinello Ruby, Domenici Lavinia, Pignata Sandro, Mangili Giorgia, Cormio Gennaro

机构信息

Complex Operating Unit Obstetrics and Gynaecology, Ospedale Civile di San Donà di Piave-Venezia, AULSS4 Veneto Orientale, 30027 San Donà di Piave, Italy.

Radiation Oncology Section, Department of Medicine and Surgery, Perugia General Hospital Sant'Andrea delle Fratte, University of Perugia, 06156 Perugia, Italy.

出版信息

Cancers (Basel). 2024 May 31;16(11):2102. doi: 10.3390/cancers16112102.

DOI:10.3390/cancers16112102
PMID:38893221
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11171216/
Abstract

Since they are very rare tumors, lymphomas of the vulva are often not properly recognized. Patients with vulvar lymphoma are generally elderly and the classical manifestation of the disease is a vulvar mass. No significant age differences have been found between primary and secondary lymphoma. To make a correct diagnosis, it is therefore necessary to use not only histological examination but also the genetic and molecular profile in order to establish optimal therapeutic management. Literature analysis confirm the good prognosis of this disease.

摘要

由于外阴淋巴瘤是非常罕见的肿瘤,因此常常未得到正确诊断。外阴淋巴瘤患者通常为老年人,该病的典型表现是外阴肿块。原发性和继发性淋巴瘤之间未发现明显的年龄差异。因此,为了做出正确诊断,不仅需要进行组织学检查,还需要了解基因和分子特征,以便制定最佳的治疗方案。文献分析证实了这种疾病的良好预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe8/11171216/2afc459bafcf/cancers-16-02102-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe8/11171216/2afc459bafcf/cancers-16-02102-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe8/11171216/2afc459bafcf/cancers-16-02102-g001.jpg

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本文引用的文献

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The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms.《世界卫生组织造血与淋巴组织肿瘤分类》第五版:淋巴肿瘤。
Leukemia. 2022 Jul;36(7):1720-1748. doi: 10.1038/s41375-022-01620-2. Epub 2022 Jun 22.
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The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.《PRISMA 2020声明:报告系统评价的更新指南》
Syst Rev. 2021 Mar 29;10(1):89. doi: 10.1186/s13643-021-01626-4.
3
Vulvar Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma.
外阴原发性皮肤 CD8+侵袭性亲表皮细胞毒性 T 细胞淋巴瘤。
Int J Gynecol Pathol. 2021 May 1;40(3):229-233. doi: 10.1097/PGP.0000000000000648.
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Cutaneous T-cell lymphoma of the vulva.外阴皮肤T细胞淋巴瘤
Am J Obstet Gynecol. 2020 Nov;223(5):760-761. doi: 10.1016/j.ajog.2020.03.040. Epub 2020 Apr 13.
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Primary diffuse large B cell lymphoma of the vulva-Two new cases of a rare entity and review of the literature.外阴原发性弥漫性大B细胞淋巴瘤——两例罕见病例报告及文献复习
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Painless Vulvar Masses as Initial Manifestation of Marginal Zone Lymphoma.以无痛性外阴肿物为首发表现的边缘区淋巴瘤
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J Low Genit Tract Dis. 2017 Apr;21(2):e26-e27. doi: 10.1097/LGT.0000000000000296.
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Treatment of Diffuse Large B-Cell Lymphoma.弥漫性大B细胞淋巴瘤的治疗
J Clin Exp Hematop. 2016;56(2):79-88. doi: 10.3960/jslrt.56.79.
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Lymphoma.淋巴瘤
Prim Care. 2016 Dec;43(4):661-675. doi: 10.1016/j.pop.2016.07.012.
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The 2016 revision of the World Health Organization classification of lymphoid neoplasms.《世界卫生组织淋巴组织肿瘤分类(2016年修订版)》
Blood. 2016 May 19;127(20):2375-90. doi: 10.1182/blood-2016-01-643569. Epub 2016 Mar 15.