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[海马体和海马旁回对于正常及紊乱记忆功能的重要性]

[Importance of the hippocampus and parahippocampus with reference to normal and disordered memory function].

作者信息

Salzmann E

机构信息

Abteilung Neurobiologie, Max-Planck-Institut für biophysikalische Chemie.

出版信息

Fortschr Neurol Psychiatr. 1992 Apr;60(4):163-76. doi: 10.1055/s-2007-999137.

DOI:10.1055/s-2007-999137
PMID:1601385
Abstract

For decades there have been differing, partly controversial ideas concerning the function of the hippocampus. They were newly stimulated by the discovery of the widespread neocortical connexions of the adjacent parahippocampus, which itself is closely interconnected via its anterior part with the hippocampus. All theories have in common that they conceive these areas to be sites for the integration of complex information. However, some of the observations regarding their role in various memory functions are very contradictory. The present article gives a survey of the current state of knowledge concerning anatomy, physiology and pathophysiology of these cerebral areas. It appears that hippocampus and parahippocampus play a significant part in the regulation of selective attention and expectation. Thus they might also influence the process of comparison and valuation which modulates the access to neocortical associative information stores.

摘要

几十年来,关于海马体的功能一直存在不同的、部分有争议的观点。相邻海马旁回广泛的新皮质连接的发现重新激发了这些观点,海马旁回本身通过其前部与海马体紧密相连。所有理论的共同之处在于,它们都认为这些区域是复杂信息整合的场所。然而,关于它们在各种记忆功能中作用的一些观察结果非常矛盾。本文综述了有关这些脑区的解剖学、生理学和病理生理学的当前知识状态。海马体和海马旁回似乎在选择性注意和期望的调节中起着重要作用。因此,它们也可能影响比较和评估过程,而这一过程调节着对新皮质联想信息存储的访问。

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