Kennedy Sean E, Henry Richard L, Rosenberg Andrew R
Department of Nephrology, Sydney Children's Hospital, New South Wales, Australia.
J Paediatr Child Health. 2005 Jul;41(7):382-3. doi: 10.1111/j.1440-1754.2005.00640.x.
Recently published reports suggest that the combination of aminoglycosides with ceftazidime may increase the risk of renal disease in cystic fibrosis. We describe a case of unusually severe acute tubular necrosis occurring in an adolescent with cystic fibrosis receiving i.v. gentamicin plus ceftazidime and discuss the possible mechanisms.
最近发表的报告表明,氨基糖苷类药物与头孢他啶联合使用可能会增加囊性纤维化患者患肾病的风险。我们描述了一例发生在一名接受静脉注射庆大霉素加头孢他啶的囊性纤维化青少年患者身上的异常严重的急性肾小管坏死病例,并讨论了可能的机制。