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皮质发育:产生细胞多样性的艺术。

Cortical development: the art of generating cell diversity.

作者信息

Götz Magdalena, Sommer Lukas

机构信息

GSF, National Research Centre for Environment and Health, Institute for Stem Cell Research, Neuherberg/Munich, Germany.

出版信息

Development. 2005 Aug;132(15):3327-32. doi: 10.1242/dev.01931.

Abstract

The fascinating question of how the enormous diversity of neuronal and glial cells in the cerebral cortex is generated during development was recently discussed at a meeting on cortical development and stem cells in Greece. What emerged from this meeting is an equally fascinating answer, namely that precursor diversity at rather early stages of development anticipates later cell type diversity.

摘要

最近在希腊举行的一次关于皮质发育和干细胞的会议上,探讨了一个引人入胜的问题:在发育过程中,大脑皮质中神经元和神经胶质细胞的巨大多样性是如何产生的。这次会议得出的一个同样引人入胜的答案是,在发育相当早期阶段的前体细胞多样性预示着后期的细胞类型多样性。

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